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EC number: 417-560-0 | CAS number: 67881-98-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Surface tension
Administrative data
- Endpoint:
- surface tension
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 20 November 2008 to 19 March 2009
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- This study was conducted according to the relevant international Guidelines (OECD 115 and OJEC Guideline A.5) using the ring method. The study report provided enough information to clarify the validity of the study and make the methodolgy used wholly reproduceable.
Cross-referenceopen allclose all
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to other study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 009
- Report date:
- 2009
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 115 (Surface Tension of Aqueous Solutions)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.5 (Surface Tension)
- Deviations:
- no
- Principles of method if other than guideline:
- N/A
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- UK GLP Regulation (1992)
- Type of method:
- ring method
Test material
- Reference substance name:
- -
- EC Number:
- 417-560-0
- EC Name:
- -
- Cas Number:
- 67881-98-5
- Molecular formula:
- C11H22NO6P
- IUPAC Name:
- trimethyl[2-({2-[(2-methylprop-2-enoyl)oxy]ethyl phosphonato}oxy)ethyl]azanium
- Details on test material:
- - Name of test material (as cited in study report): HEMA-PC (2-Methacryloyloxyethyl-2'-(trimethylammoniumethyl) phosphate
- Substance type: Pure Active Substance
- Physical state: Solid
- Analytical purity: 99 % (98-101 %)
- Impurities (identity and concentrations): 0.1 % by area (HPLC)
- Purity test date: 29 September 2008
- Lot/batch No.: SS148076
- Expiration date of the lot/batch: 27 October 2009 (lab default)
- Stability under test conditions: Stable
- Storage condition of test material: Under nitrogen at -20 degrees celsius in the dark.
- Other: N/A
Constituent 1
Results and discussion
Surface tension
- Surface tension:
- 72.01 mN/m
- Temp.:
- 20.1 °C
- Conc.:
- 1 g/L
Any other information on results incl. tables
Calibration of Tensiometer
The calibration of the tensiometer with Milli-RO water at a temperature of 24.8°C gave a
mean surface tension value of 71.88 mN/m, with a coefficient of variation of 0.2%. The
literature value of the surface tension of water at 24.8°C is 71.93 mN/m. The correction
factor was therefore determined to be 1.001.
See Table 1.
Measurement of Surface Tension
Triplicate determinations of the surface tension of duplicate aliquots of the test item gave
mean surface tension values of 71.95 and 71.93 mN/m. These values were corrected using
the calibration factor to give surface tension values of 72.02 and 72.00 mN/m.
The overall mean corrected surface tension of HEMA-PC was therefore determined to be
72.01 mN/m.
See Table 2.
Table 1. Calibration of Tensiometer
Temperature (oC) |
Surface Tension (mN/m) |
Mean Reading (mN/m) |
Coefficient of Variation (%) |
24.8 |
72.06 |
71.88 |
0.2 |
71.82 |
|||
71.77 |
Table 2. Surface Tension of HEMA-PC
Replicate |
Surface Tension (mN/m) |
Temperature (oC) |
Mean Surface Tension (mN/m) |
Coefficient of Variation (%) |
Corrected Surface Tension * (mN/m) |
Overall Mean Corrected Surface Tension (mN/m) |
A |
72.11 |
20.1 |
71.95 |
0.2 |
72.02 |
72.01 |
71.85 |
||||||
71.88 |
||||||
B |
72.14 |
20.1 |
71.93 |
0.2 |
72.00 |
|
71.84 |
||||||
71.82 |
* Corrected for water calibration factor (1.001)
Applicant's summary and conclusion
- Conclusions:
- Surface tension was successfully determined for HEMA-PC
Surface Tension = 72.01 mN/m (Coefficient of Variation = 0.2 %) - Executive summary:
Surface tension was successfully determined for HEMA-PC according to OECD Guideline 115.
Surface Tension = 72.01 mN/m (Coefficient of Variation = 0.2 %)
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