Registration Dossier
Registration Dossier
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EC number: 203-696-6 | CAS number: 109-69-3
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 0.056 mg/L
- Assessment factor:
- 100
- Extrapolation method:
- assessment factor
- PNEC freshwater (intermittent releases):
- 0.756 mg/L
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 0.006 mg/L
- Assessment factor:
- 1 000
- Extrapolation method:
- assessment factor
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 10 mg/L
- Assessment factor:
- 100
- Extrapolation method:
- assessment factor
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 1.971 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 0.197 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 0.367 mg/kg soil dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
According to key study results of toxicity tests on invertebrates, fish, algae and microorganisms, acute harmfulness to aquatic organisms was observed with the most sensitive organism group (LC50 values = 75.6 mg/L - fish).
In a chronic study under semi-static conditions, the NOEC(21d) for Daphnia magna resulted in a value of 5.6 mg/L. Chronic results were available for 1-chlorobutane (daphnia and algae), hence an assessment factor of 100 was applied for the PNEC aqua (freshwater) derivation and an assessment factor of 1000 for the PNEC aqua (marine water) derivation on account of the unavailability of a chronic fish study.
The calculation of PNEC aqua (intermittent release) is based on the most sensitive acute study available (fish) with an LC50(96h) value of 75.6 mg/L. The PNEC sewage treatment plant is based on the low toxicity to microorganisms (EC50(3h)>1000 mg/L).
The substance will be predominantly found in the water and air compartment and no exposure of soil and sediments are expected.
The PNECs for sediment and soil were calculated according to the equilibrium partitioning method as described in the REACH Guidance Document R.10 (May 2008), using Equation R.10-2, R.10-3 and R.10-5 respectively.
An experimentally derived BCF value of <21 shows no significant bioaccumulation in Cyprinus carpio.
Conclusion on classification
The data is conclusive, but not sufficient for classification according to DSD (67/548/EEC) and CLP (1272/2008/EC).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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