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Diss Factsheets
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EC number: 205-443-5 | CAS number: 140-93-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Method details lacking. considered to be based on visual solubility without analysis.
Note that the substance is supplied in water at over 40% actives. When diluted, hydrolysis occurs. - Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Type of method:
- flask method
- Water solubility:
- 462 g/L
- Temp.:
- 0 °C
- pH:
- 10
- Water solubility:
- 482 g/L
- Temp.:
- 10 °C
- pH:
- 10
- Water solubility:
- 505 g/L
- Temp.:
- 20 °C
- pH:
- 10
- Conclusions:
- Although the solid will 'disappear' in water, the visual assessment does not differentiate between solution or hydrolysis.
- Endpoint:
- water solubility
- Remarks:
- Investigation into behaviour in water at different pH
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with generally accepted scientific standards and described in sufficient detail
- Justification for type of information:
- The study was designed to establish behaviour in water.
Other data included as 'Weight of Evidence' demonstrate that up to 500 g/l will appear to dissolve, but it is unknown whether hydrolysis has a part in this.
This study involved assessing stability of solutions in water at gastric and environmental pH - Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Study of the decomposition of eight samples of xanthates in simulated gastric fluid; sodium isoamyl xanthate, sodium isobutyl xanthate, sodium ethyl xanthateр potassium isoamyl xanthate, potassium ethyl xanthate (PEX). sodium isopropyl xanthate (SIPX), Potassium amyl xanthate and potassium isobutyl xanthate.
The reaction between simulated gastric fluid and the xanthate salts was carried out at 0 C for reasons of safety, as the reaction was expected to occur very quickly. The reaction mixture was then allowed to warm to room temperature over 1 hour, the final temperature being 25 C. A high degree of degradation at this temperature would lead to the inference that degradation would be at least as complete, if not more so, in actual gastric conditions.
Following the reaction solvent was added to produce a biphasic mixture, and the resulting organic phases were analysed by GC-MS to confirm the presence of the corresponding alcohols. These alcohols were quantified by comparison to known standards in order to confirm the completeness of the reaction, and to show that these salts behave in the same way under these reaction conditions.
It was not possible to detect carbon disulphide, considered to be due to rapid degradation in water to sulphur dioxide and carbon dioxide - GLP compliance:
- no
- Conc. based on:
- test mat.
- Loading of aqueous phase:
- 100 mg/L
- Temp.:
- 0 °C
- pH:
- ca. 1.5
- Remarks on result:
- not determinable
- Remarks:
- Rapid hydrolysis. Not possible to detect parent material.
- Conclusions:
- Although public data and anecdotal evidence suggests a high level of solubility in water based on visual assessment when mixing in water in excess of 500 g/l, solubility assessment at concentrations relevant for biological and environmental exposure demonstrate rapid hydrolysis meaning that the parent compound was not possible to detect in water.
This study uses the same source data as the key Hydrolysis endpoint.
Referenceopen allclose all
Description of key information
Although a high level of water solublity was observed under neutral / environmental pH, it is considered likely that when dissolved to biologically or environmentally relvent concentrations, the substance will be unstable.
A study has been performed to assess behaviour in water at gastric pH to show rapid formation of hydrolysis products.
Key value for chemical safety assessment
- Water solubility:
- 505 g/L
- at the temperature of:
- 20 °C
Additional information
The substance mixes well in water. but will hydrolyse.
Under acid conditions, there will be rapid hydrolysis.
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