Registration Dossier
Registration Dossier
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EC number: 209-798-7 | CAS number: 593-56-6
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Well conducted study according to ASTM standard.
Data source
Reference
- Reference Type:
- publication
- Title:
- Acute bioassays and hazard evaluation of representative contaminants detected in Great Lakes fish
- Author:
- Passino DRM & Smith SB
- Year:
- 1 987
- Bibliographic source:
- Environ Toxicol Chem (6): 901-907
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: Annual Book of ASTM Standards E729-80: Standard practise of conducting acute toxicity tests with fishes, macroinvertebrates, and amphibians.
- GLP compliance:
- no
Test material
- Reference substance name:
- Methoxyammonium chloride
- EC Number:
- 209-798-7
- EC Name:
- Methoxyammonium chloride
- Cas Number:
- 593-56-6
- Molecular formula:
- CH5NO.ClH
- IUPAC Name:
- methoxyammonium chloride
- Details on test material:
- - Name of test material (as cited in study report): O-Methylhydroxylamine hydrochloride
- Analytical purity: > 96%
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test solutions
- Vehicle:
- no
Test organisms
- Test organisms (species):
- Daphnia pulex
- Details on test organisms:
- TEST ORGANISM
- Common name: water flea
- Age at study initiation: less than 24 h
- Feeding during test: none during test
- Food type: 1:1:4 mixture of four single-species green algae cultures (Chlorella vulgaris, C. pyrenoidosa, Ankistrodesmus falcatus, Chlamydomonas reinhardii) with cerophyl medium
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 48 h
Test conditions
- Test temperature:
- 17 °C
- Nominal and measured concentrations:
- - 5 different concentrations (not specified)
- Details on test conditions:
- TEST SYSTEM
- Test vessel: 150 ml test chamber
- No. of organisms per vessel: 10 neonates
- No. of vessels per concentration (replicates): 1
- No. of vessels per control (replicates): 1
- No. of vessels per vehicle control (replicates): 1
EFFECT PARAMETERS MEASURED: Immobilisation
TEST CONCENTRATIONS
- Source/preparation of dilution water: reconstituted hard water
Results and discussion
Effect concentrations
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 0.394 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
