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EC number: 256-170-3 | CAS number: 44914-03-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
60% BOD/ThOD after 11 days in an OECD 301D test
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
2-MBA was tested in a closed-bottle assay due to its volatility. It was 50% degraded by day 7 and 60.0% degraded by day 11. That further biodegradation was not seen is suspected to be due to volatility of the test substance, the distinctive odor of which could not be detected even in abiotic samples at the end of the study period. The ready biodegradability of 2-MBA is supported by data from two analogous compounds. n-Butyl acrylate (n-BA) differs from 2-MBA by the latter's additional methyl branch adjacent to the ester moiety on the alcoholic side of the molecule. Molecular weight, hydrophobicity and vapor pressure are similar between 2-MBA and n-BA. n-BA is readily biodegradable, showing 80-90% biodegradation in an OECD 310 assay. The OECD 310 assay was developed specifically to test ready biodegradation of highly volatile test compounds. The entirely linear structure of n-BA is expected to be somewhat more amenable to esterase activity and beta-oxidation than the 2-methyl branched structure of 2-MBA. The second analogous compound, isooctyl acrylate (IOA), is a UVCB substance possessing a variety of branched structures in its alcoholic domain. The alcoholic domain consists mostly (>94.0%) of C8 iso-alcohols with smaller amounts of C7 and C9. IOA is more hydrophobic, less water soluble, and of higher molecular weight than 2-MBA, implying a molecule less amenable to biodegradation. The mixed branching and lengths of the alcohol units complicates biodegradation relative to 2-MBA as the enzymatic systems must be able to process a wider variety of starting materials and intermediates. Read-across from IOA provides a conservative assessment of 2-MBA's biodegradation potential. Nevertheless, IOA was 93-95% biodegraded in a 28-day OECD 301D bioassay. The increased biodegradation of IOA relative to 2-MBA may be due in part to the lower vapor pressure of IOA, leading to decreased volatilization losses from test bottles. Based on the available data, it can be concluded that 2-MBA is readily biodegradable.
Data matrix – Analog approach |
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Target substance |
Source substance (1) |
Source substance (2) |
|
CHEMICAL NAME |
2-methylbutyl acrylate |
n-butyl acrylate |
Isooctyl acrylate |
CAS# |
44914-03-6 |
141-32-2 |
29590-42-9 |
Molecular formula |
C8H14O2 |
C7H12O2 |
C11H20O2 (on average) |
Molecular Weight |
142.2 |
128.2 |
184.3 (on average) |
PHYSICO-CHEMICAL DATA |
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Melting Point |
Experimental: ≤ -75 °C |
Not available |
Experimental: < -90 °C at 1004 hPa |
Boiling Point |
Experimental: 161.7 °C at 1013hPa |
Experimental: 147 °C at 1013hPa |
Experimental: 196.8 °C at 1016 hPa |
Density |
Experimental: 0.8886 g/cm3 at 25 °C |
Experimental: 0.9 g/cm3 at 20.0 °C |
Experimental: 0.885 g/cm3 at 20.0 °C |
Vapour Pressure |
Experimental: 1.7 hPa at 20°C |
Experimental: 5 hPa at 22.2°C |
Experimental: 1 hPa at 20 °C |
Partition Coefficient (log KOW) |
Experimental: 2.9 |
Experimental: 2.38 (at 25°C) |
Experimental: 4.5 - 4.7 |
Water Solubility |
Experimental: 316 mg/L at 23 °C |
Not available |
Experimental: 12.44 mg/L at 23.1 °C |
ENVIRONMENTAL FATE and PATHWAYS |
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Photodegradation |
QSAR: DT50 1.04 d (AOPWIN v1.92) |
Not determined |
QSAR: 17.4 - 21.4 h (AOPWIN v.1.92) |
Stability in Water |
Adaptation, readily biodegradable |
Experimental: DT50, 1100 day at pH 7, 25 °C (40CFR796.3500) |
Adaptation, readily biodegradable |
Aerobic Biodegradation |
Experimental: 60% after 11 days (OECD 301D) |
Experimental: 80 - 90% after 28 days (OECD 310) |
Experimental: 93-95% after 28 days (OECD 301D) |
Bioconcentration |
Not bioaccumulative |
Not bioaccumulative |
Not bioaccumulative |
Transport and Distribution |
Koc 263 – 302 (Calculated by TGD method) |
Experimental: Koc 40-148 (EPA OTS 796.2750) |
Experimental: Koc 650-3900 (OECD117) |
Henry's Law constant |
Experimental: 96 Pa*m3/mol at 23.1 °C |
Not determined |
Experimental: 1780 Pa*m3/mol at 23.1 °C |
ENVIRONMENTAL TOXICITY |
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Toxicity to Microorganisms (activated sludge respiration) |
Experimental: 3-hour EC50 >1000 mg/L (OECD 209) |
Experimental: 3d EC50 >150 mg/L (ASTM STP 528) |
Experimental: 3-hour EC50 >1000 mg/L (OECD 209) |
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