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EC number: 257-077-0
CAS number: 51240-95-0
Measured test substance concentrations (Stability test without test
T11032 Recovery DSW I-1 T=0
T11032 Recovery DSW I-2 T=0
T11032 Recovery DSW II-1 T=0
T11032 Recovery DSW II-2 T=0
T11032 Recovery DSW III-1 T=0
T11032 Recovery DSW III-2 T=0
T11032 Recovery DSW I-1 T=24
T11032 Recovery DSW I-2 T=24
T11032 Recovery DSW II-1 T=24
T11032 Recovery DSW II-2 T=24
T11032 Recovery DSW III-1 T=24
T11032 Recovery DSW III-2 T=24
show that despite the large increase in the loading of the test material
the soluble fraction of the parent component stays relatively stable.
Indicating that the test did indeed take place at the maximum achievable
concentration of the parent and most likely in the presence of an
increasing concentration of degradation products that were not
quantified in this study. Results also indicate that the parent
component was completely degraded after 24 hours and no longer
detectable. For this reason a semi static approach was used to replenish
the test substance and ensure a worst case scenario
Guideline study with modifications due to the difficult nature of the
test substance. Certificate of analysis present. GLP accreditation.
Analytical investigation conducted separately to test (but using
identical concentrations, medium and procedures) due to failed
analytical method during the study itself. Extended range finding work
conducted under different preparation methods to justify approach in
definitive test. See supporting studies. Correction for potential
absorbption to glass or lack of exposure due to glass absorbption cannot
be completely excluded despite a solution refreshment being carried
out.Exposure to more stable more soluble degradation products would
however likely have been sufficient. Therefore a klimisch 1 cannot be
given. Study reliable with these restrictions.
The substance can be concluded as non acutely toxic at its solubility
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