Registration Dossier
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EC number: 236-415-0 | CAS number: 13360-63-9
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
The LC50(96 hr) was 332 mg/L in an OECD TG 203 GLP study using zebra fish. In the Golden Orfe, the LC50(96 hr) was >100 mg/L when the pH was adjusted, and 21.5-31.6 mg/L whithout adjustment (pH 7.7 to 10.5 in test solution).
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 100 mg/L
Additional information
The acute toxicity of the test substance to fish (zebra fish) was examined in an OECD TG 203 study (static) under GLP conditions. The nominal concentrations were 0, 100, 220, 500, and 1000 mg/L. The analytical concentration of the three top concentrations was within +/- 10% of the nominal concentration. All fish died at the top concentration. The calculated LC50(96 hr) was 332 mg/L, based on the results of groups at 100, 220, and 500 mg/L in this study (Hoechst Marion Roussel, 1998).
ECOSAR predicts for fish an acute LC50, 96h of 23.7 mg/L for the aliphatic amine and 117 mg/L for the neutral organic (GUBDH, 2011).
In the Golden Orfe, the LC50(96 hr) was >100 mg/L when the pH was adjusted, and 21.5-31.6 mg/L whithout adjustment (pH 7.7 to 10.5 in test solution; BASF, 1983).
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