Registration Dossier
Registration Dossier
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EC number: 413-110-2 | CAS number: 135861-56-2
Short-term toxicity to fish
Administrative data
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Body responsible for the test
Data source
Reference
- Reference Type:
- other: Body responsible for the test
- Title:
- Unnamed
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: OECD GUIDELINE 203 (1984) EEC Directive 84/449 (1984) - Annex V - Method C1
- Deviations:
- not specified
- GLP compliance:
- yes
Test material
- Reference substance name:
- Body responsible for the test
- IUPAC Name:
- Body responsible for the test
- Test material form:
- other: saturated solution obtained was used as such and diluted (100 % to 25 %)
Constituent 1
Sampling and analysis
- Analytical monitoring:
- yes
Test solutions
- Vehicle:
- no
Test organisms
- Test organisms (species):
- Danio rerio (previous name: Brachydanio rerio)
Study design
- Test type:
- semi-static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 96 h
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 24 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 0.05 mg/L
- Basis for effect:
- mortality (fish)
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 0.05 mg/L
- Basis for effect:
- mortality (fish)
- Duration:
- 72 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 0.05 mg/L
- Basis for effect:
- mortality (fish)
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 0.05 mg/L
- Basis for effect:
- mortality (fish)
- Duration:
- 96 h
- Dose descriptor:
- NOEC
- Effect conc.:
- >= 0.05 mg/L
Any other information on results incl. tables
- Sublethal observations / clinical signs:
No auxiliary substance could help to solubilise the test substance.
Considering the low water-solubility of the test substance and in order to prevent impact of solid particles, the test substance was prepared as follows: a 1000 mg/L suspension was stirred for 2 hours; the substance in excess was then filtered. the saturated solution obtained was used as such and diluted (100% to 25%)
No mortality nor any abnormal behaviour were noted at any of these concentrations.
Analysis confirmed highest concentration <= limited of solubility.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not specified
- Conclusions:
- Due to its low water solubility, the test substance is not considered to be toxic to fish under the condition of the test.
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