Registration Dossier
Registration Dossier
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EC number: 204-485-1 | CAS number: 121-60-8
Dermal absorption
Administrative data
- Endpoint:
- dermal absorption in vitro / ex vivo
- Type of information:
- calculation (if not (Q)SAR)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- accepted calculation method
Data source
Reference
- Reference Type:
- other: Authoritative data base
- Title:
- Danish QSAR study for CAS No.: 121-60-8
- Author:
- Danish EPA Model
- Year:
- 2 012
- Bibliographic source:
- QSAR predictions by Danish Environmental Protection Agency (EPA)model powered by OASIS database:-
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: as mentioned below
- Principles of method if other than guideline:
- Data is from DEPA.
- GLP compliance:
- no
Test material
- Reference substance name:
- N-acetylsulphanilyl chloride
- EC Number:
- 204-485-1
- EC Name:
- N-acetylsulphanilyl chloride
- Cas Number:
- 121-60-8
- Molecular formula:
- C8H8ClNO3S
- IUPAC Name:
- 4-acetamidobenzenesulfonyl chloride
- Test material form:
- solid: crystalline
- Details on test material:
- - Name of test material (as cited in study report): N-acetylsulphanilyl chloride
- Substance type: Organic
- Physical state: Solid
Constituent 1
- Radiolabelling:
- no
Test animals
- Species:
- other: no data
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Type of coverage:
- not specified
- Vehicle:
- other: no data
Results and discussion
Percutaneous absorption
- Dose:
- 0.00200
- Remarks on result:
- other: Low dermal absorption
Applicant's summary and conclusion
- Conclusions:
- Dermal absorption of the substance N-acetyl sulphanilyl chloride is 0.00200 mg/cm2/event.This value indicates low dermal absorption.
- Executive summary:
Dermal absorption of the substance N-acetyl sulphanilyl chloride is 0.00200 mg/cm2/event.This value indicates low dermal absorption.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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