Registration Dossier
Registration Dossier
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EC number: 606-947-1 | CAS number: 221640-21-7
Melting point / freezing point
Administrative data
Link to relevant study record(s)
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2014
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 102 (Melting point / Melting Range)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.1 (Melting / Freezing Temperature)
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- other: Differential Thermal Analysis (DTA)/Differential Scanning Calorimetry (DSC)
- Melting / freezing pt.:
- 218 - 227 °C
- Decomposition:
- yes
- Decomp. temp.:
- > 227
- Remarks on result:
- other: No pressure reported
- Conclusions:
- The melting point of 1,2-Propanediamine, N1-(2-aminoethyl)-3-(4-ethoxyphenyl)-, dihydrochloride, (2S)- was found to be between 218 and 227 °C.
- Executive summary:
The melting point of1,2-Propanediamine, N1-(2-aminoethyl)-3-(4-ethoxyphenyl)-, dihydrochloride, (2S)- was tested according to OECD Guideline 102 in a DTA/DSC system with a heating rate of 1 K/min in crucible made of aluminium with perforated lid and no pressure was reported. The melting point of 1,2-Propanediamine, N1-(2-aminoethyl)-3-(4-ethoxyphenyl)-, dihydrochloride, (2S)- was found to be between 218 and 227 °C. The melting point was not reversible and the colour of the substance changed after this temperature which indicates that the product could start to decompose at this temperature.
Reference
The melting point is not reversible and the colour of the substance changed after this temperature which indicates that the product could start to decompose at this temperature.
Description of key information
The melting point of 1,2-Propanediamine, N1-(2-aminoethyl)-3-(4-ethoxyphenyl)-, dihydrochloride, (2S)- was found to be between 218 and 227 °C.
Key value for chemical safety assessment
- Melting / freezing point at 101 325 Pa:
- 222.5 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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