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EC number: 204-688-5 | CAS number: 124-19-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 23 November 2010 to 01 March 2011
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.4-D (Determination of the "Ready" Biodegradability - Manometric Respirometry Test)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 835.3110 (Ready Biodegradability)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Specific details on test material used for the study:
- - Names of test material (as cited in study report): Aldehyde C9 nonylic food grade; nonanal
- Substance type: Colourless to pale yellow liquid
- Physical state: Liquid
- Lot No: VE00120901
- Expiration date of the lot: 2011-10-14 - Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic (adaptation not specified)
- Details on inoculum:
- - Source of inoculum/activated sludge (e.g. location, sampling depth, contamination history, procedure): Fresh activated sludge from a biological waste water treatment plant treating predominantly domestic sewage was used.
- Storage conditions: Aerobic
- Storage length: The sludge was used on the same day it was collected.
- Preparation of inoculum for exposure: The sludge was collected in the morning, washed three times in the mineral medium (by centrifuging at 1000g for 10 minutes, discarding the supernatant and resuspending in mineral medium) and kept aerobic until being used on the same day.
- Concentration of sludge: Dry weight of suspended solids: 4.37 g/L
- Water filtered: No data - Duration of test (contact time):
- 61 d
- Initial conc.:
- 20.2 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- TEST CONDITIONS
- Composition of medium:
Solution A:
- KH2PO4: 8.5 g
- K2HPO4: 21.75 g
- Na2HPO4.2H2O: 33.4 g
- NH4Cl: 0.5 g
dissolved in water and made up to 1 L.
Solution B:
- CaCl2: 27.5 g
dissolved in water and made up to 1 L.
Solution C:
- MgSO4.7H2O: 22.5 g
dissolved in water and made up to 1 L.
Solution D:
- FeCl3.6H2O: 0.25 g
- HCl conc.: 1 drop
dissolved in water and made up to 1 L.
The mineral medium was prepared by mixing 50 mL of solution A and 2000 mL deionised water, adding 5 mL of each of the solutions B, C and D and making up to 5 L with deionised water.
- Test temperature: 22.2 - 23.0 °C
- pH: Initial: 7.6; Final: 7.49 - 7.50
- pH adjusted: yes (to 7.4 ± 0.2 with phosphoric acid or potassium hydroxide as appropriate)
- Aeration of dilution water: No data
- Suspended solids concentration: Dry weight: 4.37 g/L, diluted to 1.53 g/L
- Continuous darkness: No data
- Other: The water used during the study was deionised water containing less than 10 mg/L dissolved organic carbon.
TEST SYSTEM
- Culturing apparatus: Test flasks of the Oxitop were used and filled with 250 mL of the mineral medium (flasks containing the reference substance: 100 mL). Samples of test or reference substance were then added, followed by the suspended sludge.
- Number of culture flasks/concentration: 2 flasks
- Method used to create aerobic conditions: The flasks were continually stirred.
- Measuring equipment: The respirometer used during the study was an Oxitop Control System.
- Test performed in closed vessels: yes (the flasks were closed tightly with the measuring heads)
- Details of trap for CO2: Two sodium hydroxide pellets were placed in the quivers on top of each bottle.
SAMPLING
The oxygen consumption of each flask was recorded daily.
CONTROL AND BLANK SYSTEM
- Inoculum blank: Yes
- Abiotic sterile control: No
- Toxicity control: No
STATISTICAL METHODS: No data - Reference substance:
- benzoic acid, sodium salt
- Remarks:
- 99.0 mg/L
- Test performance:
- The repeatability validity criterion (not more than 20% difference between replicates) was fulfilled.
- Parameter:
- % degradation (O2 consumption)
- Value:
- 83
- Sampling time:
- 28 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 87
- Sampling time:
- 61 d
- Details on results:
- Aldehyde C9 Nonylic Food Grade underwent 83% biodegradation after 28 days (87% after 61 days) in the test conditions. The 10 day window was also fulfilled (23% biodegradation on day 1 and 71% on day 11).
Aldehyde C9 Nonylic Food Grade did not inhibit the intrinsic respiration of the inoculum at the test concentration and was therefore considered to be non-toxic to the inoculum at the test concentration. - Results with reference substance:
- Degradation of sodium benzoate exceeded 40% after 7 days and 65% after 14 days. The activity of the inoculum was thus verified (validity criterion).
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
- Conclusions:
- Aldehyde C9 Nonylic Food Grade is readily biodegradable.
Reference
Table 1:O2uptake for Aldehyde C9 Nonylic Food Grade (mg/L O2adjusted to nominal concentrations)
- |
Days |
1 |
11 |
14 |
21 |
28 |
42 |
61 |
|
O2uptake of sludge (inoculum blank) |
1a |
B1 |
5.4 |
26.9 |
29.6 |
32.3 |
36.3 |
44.4 |
55.2 |
2a |
B2 |
5.4 |
28.3 |
31.0 |
35.0 |
37.7 |
41.7 |
48.5 |
|
Mean |
B |
5.4 |
27.6 |
30.3 |
33.7 |
37.0 |
43.1 |
51.9 |
|
O2uptake of Test Substance + sludge |
3a |
C1 |
20.1 |
71.0 |
75.0 |
81.7 |
87.1 |
93.8 |
100.6 |
4a |
C2 |
17.4 |
66.8 |
72.2 |
78.9 |
84.2 |
95.0 |
104.4 |
|
O2uptake of Test Substance |
- |
C1-B |
14.7 |
43.4 |
44.7 |
48.1 |
50.1 |
50.8 |
48.8 |
- |
C2-B |
12.0 |
39.2 |
41.9 |
45.2 |
47.2 |
51.9 |
52.5 |
|
% biodegradation of test substance |
- |
D1 |
25 |
74 |
77 |
82 |
86 |
87 |
84 |
- |
D2 |
20 |
67 |
72 |
77 |
81 |
89 |
90 |
|
Mean |
D |
23 |
71 |
74 |
80 |
83 |
88 |
87 |
Calculations:
B1, B2, C1, C2: experimental O2uptake values
B = (B1+B2)/2
D1 = 100(C1-B)/ThOD*[S]
D2 = 100(C2-B)/ThOD*[S]
D = (D1+D2)/2
ThOD: 2.92 mg O2/mg
[S]: Initial test substance concentration (mg/L)
Table 2:O2uptake for sodium benzoate (mg/L O2adjusted to nominal concentrations)
- |
Days |
5 |
7 |
14 |
21 |
28 |
|
O2uptake of sludge (inoculum blank) |
1a |
B1 |
18.8 |
22.9 |
29.6 |
32.3 |
36.3 |
2a |
B2 |
20.2 |
22.9 |
31.0 |
35.0 |
37.7 |
|
Mean |
B |
19.5 |
22.9 |
30.3 |
33.7 |
37.0 |
|
O2uptake of Reference Substance + sludge |
17a |
A1 |
136.1 |
152.3 |
172.4 |
178.4 |
188.5 |
18a |
A2 |
* |
* |
* |
* |
* |
|
O2uptake of Reference Substance |
- |
A1-B |
116.6 |
129.4 |
142.1 |
144.8 |
151.5 |
- |
A2-B |
* |
* |
* |
* |
* |
|
% biodegradation of reference substance |
- |
D1 |
70 |
78 |
85 |
87 |
91 |
- |
D2 |
* |
* |
* |
* |
* |
|
Mean |
D |
70 |
78 |
85 |
87 |
91 |
Calculations:
B1, B2, A1, A2: experimental O2uptake values
B = (B1+B2)/2
D1 = 100(A1-B)/ThOD*[S]
D2 = 100(A2-B)/ThOD*[S]
D = (D1+D2)/2
ThOD: 1.67 mg O2/mg
[S]: Initial reference substance concentration (mg/L)
*: malfunction of the measuring head, not used for this study
Description of key information
The test substance was assessed for biodegradability according to OECD guideline 301F. The test substance was readily biodegradable.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
The test substance was assessed for biodegradability according to OECD guideline 301F and underwent 83% biodegradation after 28 days (87% after 61 days). The 10 day window was also fulfilled (23% biodegradation on day 1 and 71% on day 11). The test substance is regarded as readily biodegradable according to this test. Similar high levels of degradation were observed in an inherent 302C study (84% after 28 days).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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