Registration Dossier
Registration Dossier
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EC number: 700-330-1 | CAS number: 433733-92-7
Repeated dose toxicity: dermal
Administrative data
- Endpoint:
- short-term repeated dose toxicity: dermal
- Data waiving:
- exposure considerations
- Justification for data waiving:
- a short-term toxicity study does not need to be conducted because exposure of humans via the dermal route in production and/or use is not likely as based on the provided thorough and rigorous exposure assessment
- Justification for type of information:
- The substance is received onto the site and it is chemically converted into the active pharmaceutical ingredient. The substance is chemically converted into the active pharmaceutical ingredient in a system designed to ensure rigorous containment of the substance. Reaction step is carried out in closed system. Charging takes place in a ventilated keg unloading booth. The dust produced by the operation is extracted. Operators are trained in the procedure and also PSS training is performed. Personal protective clothing is specified as per PSS. The waste AHT packaging is placed into a waste container which is fitted with the appropriate WDRF label and sent for disposal.
Data source
Materials and methods
Results and discussion
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
