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Diss Factsheets

Environmental fate & pathways

Biodegradation in water: screening tests

Administrative data

Endpoint:
biodegradation in water: ready biodegradability
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1999
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1999
Report date:
1999

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
Deviations:
no
GLP compliance:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
2-Ethoxy-4-{3-[(S)-3-methy-1-(2-piperidin-1-yl-phenyl)-butylamino]-2-oxo-propyl}-benzoic acid ethyl ester
EC Number:
604-604-0
Cas Number:
147770-06-7
Molecular formula:
C29 H40 N2 O4
IUPAC Name:
2-Ethoxy-4-{3-[(S)-3-methy-1-(2-piperidin-1-yl-phenyl)-butylamino]-2-oxo-propyl}-benzoic acid ethyl ester

Study design

Oxygen conditions:
not specified
Inoculum or test system:
activated sludge, domestic (adaptation not specified)
Duration of test (contact time):
28 d

Results and discussion

% Degradation
Parameter:
% degradation (CO2 evolution)
Value:
>= 3.7 - <= 7.7
Sampling time:
28 d
Details on results:
Under the test conditions the percentage biodegradation of AGEE 623 Amidester was determined to be -5.6 % and 1.2 % after 28 days of incubation.
After determination of residual CO2 in the test flasks on day 29 biodegradation rates of 3.7 % and 7.7 % were determined.

Applicant's summary and conclusion

Interpretation of results:
under test conditions no biodegradation observed
Conclusions:
The test substance can not considered to be ready biodegradable.