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Diss Factsheets
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EC number: - | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
Studies on the toxicity of Fatty acids, C16-18 (even numbered), esters with glycerol oligomers to terrestrial organisms are not available.
The target substance is characterized by low water solubility (91.9 µg/L at 20 °C; OECD 105, column elution method), low volatilization potential (vapour pressure ≤ 0.00001 Pa at 20 °C, SPARC v4.6), a moderate to high potential for adsorption to organic soil and sediment particles (log Koc = 1.31 – 12.67, KOCWIN v2.00; MCI method) and ready biodegradability. Based on these properties, soil and sediment are expected to be the main compartments for environmental distribution.However, based on the readily biodegradability in combination with low water solubility and high adsorption potential the substance is expected to be eliminated in sewage treatment plant to a high extent. Therefore, release to the aquatic environment and subsequent exposure of the terrestrial compartment is highly unlikely. Indirect exposure of soil via irrigation or atmospheric transport is not expected based on the physico-chemical substance properties.
Furthermore the substance is expected to be rapidly biodegradated in the aquatic or terrestrial compartments if released to the environment. However, the bioavailability in sediment and soil is presumably low based on the high sorption potential and on metabolization pathways. Generally, long-chain aliphatic esters can be expected to be metabolized by microorganisms.Literature provides evidence that long-chain aliphatic esters undergo common metabolic pathways and are excreted or used as energy source for catabolism by both aquatic and terrestrial microorganisms. Therefore, the bioavailability in sediment and soil is presumably low thereby reducing the probability of chronic exposure.
Based on the high log Koc (1.31 – 12.67, KOCWIN v2.00; MCI method) indicating a potential for adsorption to soil particles, tests with soil-dwelling organisms like earthworm which allows potential uptake via surface contact, soil particle ingestion and pore water (Guidance on information requirements and chemical safety assessment, Chapter R.7c, (ECHA, 2017)) are most relevant for the evaluation of soil toxicity of Fatty acids, C16-18 (even numbered), esters with glycerol oligomers. Furthermore, no acute toxicity at > 10 mg/L and chronic or long-term effects in aquatic organisms up to the water solubility limit was observed indicating no selective toxicity for the aquatic compartment. Short-term toxicity data on soil macroorganisms is available for a structurally and chemically related source substance showing no effects on survival or biomass during the exposure period.
Thus, no further study on the effects on terrestrial organisms need to be conducted for Fatty acids, C16-18 (even numbered), esters with glycerol oligomers.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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