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EC number: 950-746-4 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Remarks:
- See the Justification of Read Across attached
- Adequacy of study:
- key study
- Study period:
- 2017
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study
- Justification for type of information:
- See the Read Across justification
- Reason / purpose for cross-reference:
- read-across: supporting information
- Reason / purpose for cross-reference:
- read-across source
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- Deviations:
- no
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- EU Method C.4-C (Determination of the "Ready" Biodegradability - Carbon Dioxide Evolution Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Specific details on test material used for the study:
- Name: Phosphoric acid, mixed decyl and octyl esters, compds. with diethanolamine
CAS No.: 68425-57-0
Physical state: white solid at 20 °C (turbid, non-pourable paste)
Batch No.: PU61810016
Re-certification date of batch: 16 June 2018
Purity: 100 % (UVCB)
Moisture, % (KF) 1,2
pH, 10% in dW 7,2
Stability: stable under test conditions
Storage condition of test material: Room temperature, protected from light - Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- Activated sludge from the municipal wastewater treatment plant Breisgauer Bucht was used as inoculum with a concentration corresponding to 30 mg dry solids per litre. The treatment plant clarifies predominantly domestic wastewater and has a capacity of 600.000 inhabitant equivalents. Sampling date of activated sludge was on 03 April 2017. The dry solid content of the activated sludge was 5.09 g/L. It was determined by weight measurements after drying at 105°C for 4 hours (mean of triplicate measurements). The activated sludge was washed twice with tap water by settling the sludge, decanting the supernatant and re-suspending the sludge.
- Duration of test (contact time):
- 28 d
- Initial conc.:
- 20 mg/L
- Based on:
- TOC
- Parameter followed for biodegradation estimation:
- CO2 evolution
- Reference substance:
- benzoic acid, sodium salt
- Key result
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 92.4
- Sampling time:
- 29 d
- Results with reference substance:
- The reference compound sodium benzoate reached the pass levels for ready biodegradability within 4 days.
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
- Conclusions:
- The degradation of the test item at the end of the test was 92.4% (28 d after acidification, mean of two replicates). The test item reached the criteria for ready biodegradability (60% of ThCO2 within a 10-d window).
- Executive summary:
In a GLP OECD 301 B study the degradation of the test item at the end of the test was 92.4% (28 d after acidification, mean of two replicates). The test item reached the criteria for ready biodegradability (60% of ThCO2 within a 10-d window). The degradation of the toxicity control after 14 days was 78.5%. The test item had no inhibitory effect on the inoculum according to the criterion of the guideline.
Reference
Results
Test item
The degradation extent of the test item at the end of the test was 92.4% (28 d after acidification, mean of two replicates). On day 11, the degradation was for the first time higher than 60%. Since begin of the 10-d window is not before day 1, the mean degradation of >60% was reached within a 10-d window. Therefore the test item reached the criteria for ready biodegradability (60% of ThCO2 within a 10-d window). In one of the three test vessels (vessel 13) significantly lower degradation values were measured, probably due to an error in the addition of the test item. The replicate was therefore regarded as an outlier and not considered in the evaluation.
Blank
The mean CO2-evolution of the blank flasks was 29.5 mg/L on day 28 after acidification.
Test parameters
- Before adding the test item, the IC in the reactor was determined, but only insignificant amounts of IC (0.22 mg/L) were found.
- The IC-concentration of the NaOH in the second CO2-absorber flasks in line, used as protective flasks, was below 7 ppm and was not considered in the data processing, because CO2 absorption from room air was its source.
- The temperature was 21.1 – 23.3°C throughout the whole study.
- The aeration rate was in the tolerated range of 1.6 – 5.5 bubbles/second (counted bubbles: 2.0 – 4.1 bubbles/second).
Criteria of validity
- The IC content in the test vessel was less than 5% of the TOC introduced with the test item.
- The CO2 evolution in the inoculum blank at the end of the test was below 40 mg/L.
- The difference of extremes of replicate values of the test item at the end of the 10-d window and at the end of the test was less than 20%.
- The biodegradation of the reference compound reached the pass level of 60% ThCO2 by day 4.
- The degradation extent in the toxicity control was above 25% in 14 days based on ThCO2.
Table 1: Ultimate biodegradation after x days [% ThCO2]
Reactor | day | 0 | 4 | 7 | 11 | 14 | 21 | 28 | 29 |
11 | test flask | 0 | 28.5 | 49.8 | 65.1 | 69.8 | 75.8 | 86.4 | 89.4 |
12 | test flask | 0 | 25.6 | 52.0 | 65.0 | 68.9 | 80.9 | 93.7 | 95.3 |
13* | test flask | 0 | 11 .1 | 25.8 | 31.3 | 34.3 | 37.5 | 35.1 | 31.9 |
4 | reference flask | 0 | 71.0 | 88.0 | 94.5 | 96.2 | 97.1 | 106.0 | 107.1 |
5 | reference flask | 0 | 73.0 | 88.2 | 97.0 | 100.3 | 104.4 | 113.2 | 113.2 |
6 | reference flask | 0 | 67.2 | 82.2 | 87.5 | 90.7 | 91.2 | 99.0 | 98.4 |
14 | Toxicity control test item & reference item |
0 | 43.2 | 67.0 | 74.7 | 78.5 | 79.7 | 88.4 | 86.8 |
Mean CO2 evolution of blank flasks after x days | |||||||||
CO2 evolution [mg/l] | 0 | 7.0 | 11.5 | 16.7 | 19.1 | 24.4 | 27.4 | 29.5 |
* outlier
Description of key information
Ready Biodegradable at 92.4% degradation (CO2 evolution).
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
- Type of water:
- freshwater
Additional information
The biodegradability was tested in Read Across on a Similar substance, according toOECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test) and EU Method C.4-C (Determination of the "Ready" Biodegradability - Carbon Dioxide Evolution Test). See the Justification of read across.
Ready Biodegradable at 92.4% degradation (CO2 evolution).
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