Reaction mass of pentyl ester butanoic acid and 2-methylbutyl ester butanoic acid

Surface tension

Link to relevant study record(s)

Reference

Endpoint:

surface tension

Type of information:

experimental study

Adequacy of study:

key study

Study period:

24 October 2019 - 29 November 2019

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.5 (Surface Tension)

Version / remarks:

31 May 2008

Qualifier:

according to guideline

Guideline:

OECD Guideline 115 (Surface Tension of Aqueous Solutions)

Version / remarks:

adopted 27 July 1995

GLP compliance:

yes (incl. QA statement)

Type of method:

OECD harmonised ring method

Specific details on test material used for the study:

Name: Reaction mass of 2-methylbutyl butyrate and pentyl butyrate
Chemical name: Pentyl butyrate (n-Amyl butyrate) – 64.74%,
2-Methylbutyl butyrate (i-Amyl butyrate) – 35.06%
Description: Clear colourless to pale yellow liquid
Purity: 99.80% (multi-constituent)
Storage conditions: Controlled room temperature (15-25 °C, ≤ 70% relative humidity)
Safety precautions: Routine safety precautions (gloves, goggles, face mask, lab coat) for unknown materials will be applied to ensure personnel health and safety.

Surface tension:

65.75 mN/m

Temp.:

21.5 °C

Conc.:

112 mg/L

The measured and corrected surface tension values of the test solution

Measurement	Temperature	Surface tension	RSD %	Mean	RSD %	Corrected surface tension
	°C	mN/m		mN/m		mN/m	mean (mN/m)
1	21.57	65.77	0.06	64.66	1.78	66.88	65.75
2	21.56	63.47	0.05			64.55
3	21.59	64.73	0.02			65.83

RSD%: relative standard deviation

The individual surface tension values of test item in aqueous solution was found to be between 63.4 and 65.8 mN/m at 21.5°C ± 0.1°C using the ring method (when each individual value represents the mean of at least five determinations for each measurement).  

The measured values were corrected with Harkins-Jordan correction factor. The measured surface tension was multiplied by the proper Φ𝑏 resulting in a corrected surface tension of 65.75 mN/m with 1.78 RSD%.

As the surface tension value of the aqueous solution of the test item (at 90% of the saturation level of the solution with approximately 3-day age) was higher than 60 mN/m, Reaction mass of 2-methylbutyl butyrate and pentyl butyrate is classified as not being a surface active substance.  

DEVIATION TO THE STUDY PLAN

The in-life phase was not audited by the Quality Assurance Unit due to technical reasons, but considering, that such in-life phases were audited regularly, this fact has no effect to the Study results.

Conclusions:

The surface tension of the test item was 65.75 mN/m, so the test item is considered as non-surfactant substance

Executive summary:

The determination of the surface tension was carried out on the test item by a Krüss K11 Tensiometer using the ring method. The surface tension value was found to be 65.75 mN/m with 1.78 RSD% at 21.5°C ± 0.1°C. As the surface tension value of the aqueous solution of the test item (at 90% of saturated level) was greater than 60 mN/m, Reaction mass of 2-methylbutyl butyrate and pentyl butyrate is classified as not being a surface active substance.

Description of key information

Study conducted to recognised testing guidelines with GLP certification.

Key value for chemical safety assessment

Surface tension:

65.75

in mN/m at 20°C and concentration in mg/L:

112

Additional information

The surface tension value was found to be 65.75 mN/m with 1.78 RSD% at 21.5°C ± 0.1°C, concentration 112 mg/L

OECD 115 guidelines state:

The measurement shall be made at approximately 20°C and shall be controlled to within ± 0.5 °C.