Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: internal guideline used, no GLP
Cross-reference
Reason / purpose for cross-reference:
reference to other study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1980
Report date:
1980

Materials and methods

Test guideline
Qualifier:
no guideline available
Deviations:
not applicable
Principles of method if other than guideline:
-
GLP compliance:
not specified
Limit test:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
4-amino-2-methylpyrimidine-5-carbonitrile
EC Number:
211-814-2
EC Name:
4-amino-2-methylpyrimidine-5-carbonitrile
Cas Number:
698-29-3
Molecular formula:
C6H6N4
IUPAC Name:
4-amino-2-methylpyrimidine-5-carbonitrile

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
intraperitoneal
Vehicle:
unchanged (no vehicle)
Doses:
no information
No. of animals per sex per dose:
5 or 10
Control animals:
not specified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
620 mg/kg bw
Based on:
test mat.
Remarks:
after 24 hours
95% CL:
>= 515 - <= 725

Any other information on results incl. tables

-

Applicant's summary and conclusion

Conclusions:
-
Executive summary:

-