Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

NOT EYE IRRITANT, based on probability of severe/moderate irritation equal to 0.31

Key value for chemical safety assessment

Eye irritation

Link to relevant study records
Reference
Endpoint:
eye irritation: in vitro / ex vivo
Type of information:
(Q)SAR
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Remarks:
QSAR
Justification for type of information:
QSAR The eye irritation QSAR prediction was assessed as adequate for regulatory purposes (Klimisch 2 – results derived from a valid QSAR model and falling into its applicability
domain, with adequate and reliable documentation /justification).
Qualifier:
no guideline followed
Principles of method if other than guideline:
QSAR
GLP compliance:
no
Irritation parameter:
other: QSAR
Remarks:
QSAR
Remarks on result:
no indication of irritation
Remarks:
NOT EYE IRRITANT, based on probability of severe/moderate irritation equal to 0.31
Interpretation of results:
GHS criteria not met
Conclusions:
NOT EYE IRRITANT, based on probability of severe/moderate irritation equal to 0.31
Executive summary:

NOT EYE IRRITANT, based on probability of severe/moderate irritation equal to 0.31


Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Additional information

Justification for classification or non-classification