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EC number: 816-311-7 | CAS number: 76589-16-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 28 Nov 2017 - 11 Jan 2018
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 018
- Report date:
- 2018
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Version / remarks:
- The maximum difference was > 15%. Nevertheless, results of a repeat study were
accepted.
Evaluation: The water solubility determination was repeated using laboratory glass ware
only, as plastic surfaces might have caused adsorption in a first study. During the repeat
study, the maximum difference was again > 15% considering results of all three
timepoints. The 24 and the 72 h timepoint, however, were reasonably close to each other.
Additionally, the 72 h timpoints of both water solubility studies were very similar to each
other. The data set of the second study showed that the equilibrium water solubility
concentration was reached. Therefore, results were accepted. The average of all values
in the second study (i.e. 119 mg/L) was considered to reflect the water solubility of the
test item. - Deviations:
- yes
- Remarks:
- None of the deviations were considered to have impacted the overall integrity of the study or the interpretation of the study results and conclusions.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Version / remarks:
- The maximum difference was > 15%. Nevertheless, results of a repeat study were
accepted.
Evaluation: The water solubility determination was repeated using laboratory glass ware
only, as plastic surfaces might have caused adsorption in a first study. During the repeat
study, the maximum difference was again > 15% considering results of all three
timepoints. The 24 and the 72 h timepoint, however, were reasonably close to each other.
Additionally, the 72 h timpoints of both water solubility studies were very similar to each
other. The data set of the second study showed that the equilibrium water solubility
concentration was reached. Therefore, results were accepted. The average of all values
in the second study (i.e. 119 mg/L) was considered to reflect the water solubility of the
test item. - Deviations:
- yes
- Remarks:
- None of the deviations were considered to have impacted the overall integrity of the study or the interpretation of the study results and conclusions.
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7840 (Water Solubility)
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
Test material
- Reference substance name:
- 2-methoxy-2-methylheptane
- EC Number:
- 816-311-7
- Cas Number:
- 76589-16-7
- Molecular formula:
- C9H20O
- IUPAC Name:
- 2-methoxy-2-methylheptane
- Test material form:
- liquid
Constituent 1
Results and discussion
Water solubility
- Key result
- Water solubility:
- 119 mg/L
- Conc. based on:
- test mat.
- Incubation duration:
- 72 h
- Temp.:
- 20 °C
- pH:
- >= 6.1 - <= 7.6
- Details on results:
- See attachment.
Applicant's summary and conclusion
- Conclusions:
- The slow-stirring flask method was applied for the determination of the water solubility of the test substance.
The water solubility of the test item at 20°C was 119 mg/L.
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