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Diss Factsheets
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EC number: 934-509-2 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Density
Administrative data
Link to relevant study record(s)
- Endpoint:
- relative density
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2008
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Manufacturer's data using standard electric measuring apparatus: 4 place digital density meter for measurement of density.
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- The density was calculated using the measurement of a known mass of the product and its volume
- GLP compliance:
- no
- Type of method:
- other: measurement of density with standard apparatus: 4 place digital density meter
- Specific details on test material used for the study:
- Name of the test material(as cited in study report):Proteol APL
batches:
0824000008
0824200013
0824200014 - Key result
- Type:
- relative density
- Density:
- 1.111 g/cm³
- Temp.:
- 20 °C
- Remarks on result:
- other: no guideline was followed
- Remarks:
- The relative density was calculated using the measurement of a volume related to a known mass -3 batches were used-. The relative density mean value of the three commercial batches tested using an electric measuring apparatus was: stated to 1.111 at 20 °C
- Conclusions:
- The relative density mean value of the three commercial batches tested using an electric measuring apparatus was: stated to 1.111 at 20 °C
- Executive summary:
No guidline was followed
The relative density was calculated using the measurement of a volume related to a known mass
3 Batches were used
The relative density was stated to 1.111
- Endpoint:
- relative density
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2011
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Manufacturer's data using standard electric measuring apparatus: digital density meter for measurement of density.
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- The density was calculated using the measurement of a known mass of the product and its volume
- GLP compliance:
- no
- Type of method:
- other: measurement of density with standard apparatus: a digital density meter is an instrument that is designed to measure and display in numerical digits the relative density (i.e., mass per mass) of a liquid.
- Specific details on test material used for the study:
- Name of the test material (as cited in study report): Proteol APL green
batches:
2308JG
2629JG
2636JG
and
Name of the test material (as cited in study report):Proteol APL
batches:
T10841
T11921
T12621 - Key result
- Type:
- relative density
- Density:
- 1.11 g/cm³
- Temp.:
- 20 °C
- Remarks on result:
- other: no guideline was followed
- Remarks:
- The relative density was calculated using the measurement of a volume related to a known mass -6 batches were used-. The relative density mean value of the six batches tested using an electric measuring apparatus was: stated to 1.11 at 20 °C
- Conclusions:
- The relative density mean value of the six batches tested using an electric measuring apparatus was: stated to 1.11 at 20 °C
- Executive summary:
No guidline was followed
The relative density was calculated using the measurement of a volume related to a known mass
6 Batches were used
The relative density was stated to 1.11
- Endpoint:
- relative density
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 109 (Density of Liquids and Solids)
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- EU Method A.3 (Relative Density)
- Principles of method if other than guideline:
- The relative density at 20° C was measured at the PAAR densimeter. For each of the three batches, two measurements were taken.
- GLP compliance:
- no
- Type of method:
- other: PAAR density meter
- Specific details on test material used for the study:
- Batch numbers:
-1313600046
-1333100039
-1324100061 - Key result
- Type:
- relative density
- Density:
- >= 1.1 - <= 1.105 g/cm³
- Temp.:
- 20 °C
- Conclusions:
- The relative density was stated to be 1.103 +/- 0.005 g/cm3 at 20°C.
- Executive summary:
The relative density was stated to be 1.103 +/- 0.005 g/cm3 at 20°C.
- Endpoint:
- relative density
- Type of information:
- read-across based on grouping of substances (category approach)
- Adequacy of study:
- weight of evidence
- Justification for type of information:
- REPORTING FORMAT FOR THE CATEGORY APPROACH
Registered substance (as identified in Section 1.1 identification) has similar chemical structure as the others members of the Category "Amino Acid Alkyl Amides, Sodium or Potassium Salts" (the source chemicals).
The category “Amino Acid Alkyl Amides, Sodium or Potassium Salts” has been developed and evaluated to cover the assessment of the intrinsic properties of several similar substances within the context of REACH Regulation. The Category includes sodium or potassium salts of amino acid alkyl amides, with a carbon chain length range of C6-C16 and an aminoacidic pool of not selected aminoacids reflecting the natural distributions of aminoacids in various vegetables and cereals.
1. HYPOTHESIS FOR THE CATEGORY APPROACH (ENDPOINT LEVEL)
The Category has been built up considering the common chemical structure of its members. They are UVCB substances and they share the following features:
- they are salts of amino acid alkyl amides
- they are sodium or potassium salts
- the carbon chain length ranges between C6 and C16
- the carbon chain derives from cocoyl or lauroyl fatty acids
- the aminoacidic part of the molecules comes from a pool of aminoacids
- the aminoacids pool reflects the natural distributions of aminoacids in various vegetables and cereals.
Overall, the Category was formed on the hypothesis that substances sharing this common chemical structure can be considered analogues and can share intrinsic properties too. No
trends in properties is expected, except for those physicochemical properties depending on the carbon chain length.
2. CATEGORY APPROACH JUSTIFICATION
These substances share (i) eye damage and (ii) the absence of significant systemic toxicity. - Key result
- Type:
- relative density
- Density:
- ca. 1 g/cm³
- Remarks on result:
- other: relative density values are available for category members: (i) 1.1 g/cm3, (ii) 1.1-1.105 g/cm3.
- Remarks:
- relative density values are available for category members: (i) 1.1 g/cm3, (ii) 1.1-1.105 g/cm3.
- Conclusions:
- A collection of the relative density values is available for category members. Considering these values the registered substance has a relative density of 1 g/cm³.
- Executive summary:
The category “Amino Acid Alkyl Amides, Sodium or Potassium Salts” was formed on the hypothesis that substances sharing common chemical structure can be considered analogues and can share intrinsic properties too.
Based on this assumption, this property may be assessed using available data for the category members.
The category has been assessed for members characterized by:
- sodium or potassium salts
- the carbon chain length ranges between C6 and C16
- the aminoacids pool reflects the natural distributions of aminoacids in various vegetables and cereals.
Referenceopen allclose all
Description of key information
Category members (Amino Acid Alkyl Amides, Sodium or Potassium Salts) have density values higher than 1 g/cm3.
Key value for chemical safety assessment
Additional information
A collection of the relative density values is available for category members. All found values are listed below.
EC number |
Density (g/cm³) |
S1 - EC: 918-984-3 |
>= 1.1 g/cm³ |
S2 - EC: 927-837-2 |
>= 1.1 - <= 1.105 g/cm³ |
Overall, registered substance has a relative density of 1 g/cm³
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.