Registration Dossier
Registration Dossier
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EC number: 202-941-4 | CAS number: 101-42-8
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- (Q)SAR
- Adequacy of study:
- key study
- Study period:
- 2018
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
- Justification for type of information:
- Biodegradability was estimated using the BIOWIN™ v4.10 module of EPI Suite™ v.4.11. BIOWIN™ estimates aerobic and anaerobic biodegradability of organic chemicals using 7 different models. Two of these are the original Biodegradation Probability Program (BPP™).
Data source
Reference
- Reference Type:
- other: Result of QSAR calculations
- Title:
- Unnamed
- Year:
- 2 018
- Report date:
- 2018
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Biodegradation was estimated using the BIOWIN™ v4.10 module of EPI Suite™ v.4.11. BIOWIN™ estimates aerobic and anaerobic biodegradability of organic chemicals using 7 different models. Two of these are the original Biodegradation Probability Program (BPP™). The seventh and newest model estimates anaerobic biodegradation potential. The Estimation Programs Interface EPI Suite™ was developed by the US Environmental Protection Agency's Office of Pollution Prevention and Toxics and Syracuse Research Corporation (SRC).
Test material
- Reference substance name:
- Fenuron
- EC Number:
- 202-941-4
- EC Name:
- Fenuron
- Cas Number:
- 101-42-8
- Molecular formula:
- C9H12N2O
- IUPAC Name:
- fenuron
- Test material form:
- not specified
Constituent 1
Results and discussion
% Degradation
- Key result
- Remarks on result:
- not readily biodegradable based on QSAR/QSPR prediction
Applicant's summary and conclusion
- Conclusions:
- The substance is considered not readily biodegradable
- Executive summary:
Probability of Rapid Biodegradation (BIOWIN v4.10):
Biowin1 (Linear Model) : 0.7975
Biowin2 (Non-Linear Model) : 0.9224
Expert Survey Biodegradation Results:
Biowin3 (Ultimate Survey Model): 2.8583 (weeks )
Biowin4 (Primary Survey Model) : 3.6157 (days-weeks )
MITI Biodegradation Probability:
Biowin5 (MITI Linear Model) : 0.2655
Biowin6 (MITI Non-Linear Model): 0.1715
Anaerobic Biodegradation Probability:
Biowin7 (Anaerobic Linear Model): 0.4180
Ready Biodegradability Prediction: NO
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