Registration Dossier
Registration Dossier
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EC number: 218-451-9 | CAS number: 2155-60-4
Basic toxicokinetics
Administrative data
- Endpoint:
- basic toxicokinetics
- Type of information:
- other: expert statement
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- Theoretical assessment taking all currrently available relevant information into account, based on the REACH Guidance: Guidance on Information Requirements and Chemical Safety Assessment, Chapter R.7c Endpoint specific guidance. Since this is a theoretical assessment, the Klimisch value cannot be 1.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 016
- Report date:
- 2017
Materials and methods
- GLP compliance:
- no
Test material
- Reference substance name:
- Dibutyl itaconate
- EC Number:
- 218-451-9
- EC Name:
- Dibutyl itaconate
- Cas Number:
- 2155-60-4
- Molecular formula:
- C13H22O4
- IUPAC Name:
- 1,4-dibutyl 2-methylidenebutanedioate
- Test material form:
- liquid
Constituent 1
Results and discussion
Main ADME results
- Type:
- absorption
- Results:
- For risk assessment purposes, 50% is used for oral and dermal absorption and 100% for inhalation absorption.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
