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EC number: 242-044-5 | CAS number: 18162-84-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Hydrolysis
Administrative data
Link to relevant study record(s)
- Endpoint:
- hydrolysis
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2015-03-13
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.7 (Degradation: Abiotic Degradation: Hydrolysis as a Function of pH)
- Principles of method if other than guideline:
- Screening method based on 1H-NMR spectroscopy.
- GLP compliance:
- no
- Remarks:
- ISO 9001:2008
- Analytical monitoring:
- not specified
- Buffers:
- - pH: 4
CertiPur, Citric acid + hydrochloric acid + sodium hydroxide, company Merck
- pH: 7
Baker Analyzed, Potassium dihydrogen phosphate + disodiumhydrogen phosphate, company J. T. Baker
- pH: 9
CertiPur, Boronic acid + potassium chloride + sodium hydroxide, company Merck - Transformation products:
- no
- pH:
- 4
- Temp.:
- 25 °C
- Remarks on result:
- other: Half-life <<2 minutes
- pH:
- 7
- Temp.:
- 25 °C
- Remarks on result:
- other: Half-lfe <<2 minutes
- pH:
- 9
- Temp.:
- 25 °C
- Remarks on result:
- other: Half-life <<2 minutes
- Other kinetic parameters:
- None determined.
- Details on results:
- A determination of the hydrolysis kinetics was not possible since suitable samples for 1H NMR spectroscopic measurements could not be prepared because of very fast hydrolysis and precipitation of solids. The half-life times were thus assumed to be much smaller than 2 min.
- Conclusions:
- Hydrolysis half-lives of <<2 min at pH 4, pH 7 and pH 9 and 25°C were determined in a non-guideline study conducted according to generally accepted scientific principles. The result is considered to be reliable.
- Endpoint:
- hydrolysis
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Justification for type of information:
- Please refer to the attached justification below and the overall justification for grouping of substances attached in IUCLID Section 13.
- Reason / purpose for cross-reference:
- read-across source
- Transformation products:
- not specified
- pH:
- 4
- Temp.:
- 25 °C
- Remarks on result:
- other: Half-life <<2 minutes
- pH:
- 7
- Temp.:
- 25 °C
- Remarks on result:
- other: Half-lfe <<2 minutes
- pH:
- 9
- Temp.:
- 25 °C
- Remarks on result:
- other: Half-life <<2 minutes
- Other kinetic parameters:
- None determined.
Referenceopen allclose all
Description of key information
Hydrolysis half-life: < 2 min (EU method C.7)
Key value for chemical safety assessment
Additional information
No data on the hydrolysis of chloro(dimethyl)octylsilane (CAS 18162-84-0) are available. Therefore good quality data from the similar substance trichloro(trimethylpentyl)silane (CAS 18379-25-4) were read across. Details on the read across justification can be found in the attached justification in the respective target entry and in the overall justification for grouping of substances attached in IUCLID Section 13.
The hydrolysis study for the trichloro(trimethylpentyl)silane (CAS 18379-25-4) was performed according to EC test guideline C.7 (in analogy to OECD test guideline 111). A determination of the solubility of the read across substance in water and its hydrolysis kinetics was not possible since suitable samples for kinetic 1H NMR spectroscopic measurements could not be prepared due to very fast hydrolysis and precipitation of solids. The half-life was thus assumed to be much lower than 2 min. This result is in line with other chlorosilanes, for which measured data are available (see supporting information).
On this basis the hydrolysis of the substance is expected to be very fast and the hydrolysis products are (dimethyl)octylsilanol and hydrochloric acid.
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