Registration Dossier
Registration Dossier
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EC number: 252-036-3 | CAS number: 34451-19-9
Endpoint summary
Administrative data
Description of key information
The most sensitive organism tested was the fish Danio rerio. The 96-h LC50 of 42.8 mg/L (measured concentration) was determined in an acute toxicity test according to OECD 203 and in compliance with GLP (Hooftman et al., 1992).
Additional information
Data describing the acute toxicity of butyl-(S)-lactate to aquatic organisms are available for fish, aquatic invertebrates, algae and microorganisms. The studies were conducted according to the relevant OECD test guidelines.
The toxicity of butyl-(S)-lactate towards algae was tested in a growth inhibition study according to OECD guideline 201 under GLP. The effect concentrations were determined as follows: 72-h NOEC = 31.25 mg/L and 72-h LOEC = 78.12 mg/L for Pseudokirchneriella subcapitata (Schwartz, 2017).
The acute immobilisation tests with Daphnia magna revealed a 48-h EC50 of 296 mg/L (Hooftman 1992) and a 48-h EC50 of 423 mg/L (Bowmer 1998). The results from the activated sludge respiration inhibition test with microorganisms according to the OECD guideline 209 indicated no hazard.
The most sensitive organism tested was the fish Danio rerio (LC50 (96 h) = 42.8 mg/L, measured concentration).
As the publication from Bowmer (1998) shows serious documentation deficiencies it is unclear (yet quite likely) whether the data source is same as in Hooftman et al. (1992). Reported effect values based on nominal concentrations are identical.
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