Registration Dossier
Registration Dossier
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EC number: 235-546-0 | CAS number: 12270-13-2
Endpoint summary
Administrative data
Description of key information
Information from ready biodegradability tests according to OECD 301 are not available. Data from an inherent biodegradability according to OECD 302 B indicates rapid removal of the test substance from the test solution by adsorption to sludge, but a final conclusion regarding biodegradation is not possible (Dietschy, 1992). Therefore, the results from determination of the biological oxygen demand after 5 days (BOD5) and the chemical oxygen demand (COD) are used in the assessment of the test substance (Kronenberg, 1991 & 1992).
If substantial degradation occurs within a short time period, the situation may be compared with the criterion BOD5/COD ≥ 0.5. In this case, a compound can be considered readily degradable. As the BOD5/COD-ratio of the test substance is 0.003, the test substance cannot be considered readily/rapidly biodegradable.
Schnalke et al. (1993) conducted additional tests in accordance with OECD 303 A (Activated Sludge Units). A high initial adsorption of the test substance to sludge could be demonstrated. However, over the total test duration (31 days) the test substance did not accumulate in the sludge. At the end of the test less than 20 % of the total amount was detected in sludge, and less than 6 % of the total test substance was released via the effluent. As only the parent substance was analysed and degradation products were not considered, complete degradation of the test substance could not be demonstrated.
In the subsequent degradation test that Schnalke et al. (1993) conducted according to OECD 302 C (MITI II Test) with non-adapted and adapted sewage sludge from the Husmann units, the test substance did not degrade (0 % after 20 days).
Additional information
This information is used in a read-across approach in the assessment of the substance to be registered.
For justification of read-across please refer to the read-across report attached to IUCLID section 13.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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