Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 269-105-9 | CAS number: 68187-54-2 This substance is identified in the Colour Index by Colour Index Constitution Number, C.I. 77865.
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- no hazard identified
Marine water
- Hazard assessment conclusion:
- no hazard identified
STP
- Hazard assessment conclusion:
- no hazard identified
Sediment (freshwater)
- Hazard assessment conclusion:
- no hazard identified
Sediment (marine water)
- Hazard assessment conclusion:
- no hazard identified
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- no hazard identified
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
Conclusion on classification
Tin antimony grey cassiterite is a poorly soluble inorganic substance. In accordance with ECHA Guidance on the Application of the CLP Criteria (V 5.0, July 2017), “where the compound is sufficiently poorly soluble that the levels dissolved following normal attempts at solubilisation do not exceed the available L(E)C50, it is the rate and extent of transformation, which must be considered.”
The release of antimony, tin and vanadium in environmental media at pH 6 and 8 was determined in an OECD transformation/dissolution test (Klawonn, 2018) with the higher release at pH 8.
Short-term (acute) aquatic hazard:
In accordance with ECHA Guidance on the Application of the CLP Criteria (V 5.0, July 2017), “A poorly soluble substance is evaluated for classification by comparing the dissolved metal ion level resulting from the TDp at 7d, at a loading rate of 1 mg/l with the acute ERV as determined for the (soluble) metal ion.”
The release of antimony, tin and vanadium from the pigment at a loading of 1 mg/L at pH 8 after 7 days results in concentrations of 0.40 µg/L, 5.71 µg/L and 0.18 µg/l, respectively, and are thus significantly lower (more than hundredfold up to more than thousandfold) than the corresponding acute Ecotoxicity reference levels (ERVs) (Sb = > 1770µg/L (EU, 2008), Sn = 9800 µg/L and V = 693 µg/L (MECLAS v 5.2)). Applying the concept of additivity, the sum of the respective ratios of dissolved metal ion concentrations in the T/Dp (loading of 1 mg/L, 7 d, pH 6 and pH 8) and corresponding acute ERVs is also well below 1 (< 0.01). Thus, the pigment does not meet classification criteria for an acute aquatic hazard under CLP.
Two supporting non-GLP studies on the acute toxicity of the dispersed pigment on zebrafish (OECD TG 203) and Daphnia magna (OECD TG 202) provide further evidence on the low potential for acute aquatic toxicity since effects were not observed at 100 mg/L (nominal, dispersed) and the respective LC/EC50 values are estimated with > 100 mg/L (nominal, dispersed). Thus, according to Table 4.1.0 (a) of Regulation (EC) No 1272/2008, tin antimony grey cassiterite would also not meet criteria for an acute aquatic hazard.
Thus, in accordance with Figure IV.4 “Classification strategy for determining acute aquatic hazard for metal compounds” of ECHA Guidance on the Application of the CLP Criteria (V 5.0, July 2017) and section 4.1.2.10.2. of Regulation (EC) No 1272/2008, classification for acute (short-term) aquatic hazard is not required for tin antimony grey cassiterite.
Long-term (chronic) aquatic hazard:
The release of antimony, tin and vanadium from the pigment at a loading of 1 mg/L at pH 8 after 28 days results in concentrations of 0.61 µg/L, 8.89 µg/L and 0.21 µg/l, respectively, and are significantly lower (more than hundredfold up to more than thousandfold) than respective chronic toxicity levels (Sb = > 1000µg/L (EU, 2008), Sn = 1001 µg/L and V = 76 µg/L (MECLAS v 5.2)). Applying the concept of additivity, the sum of the respective ratios of dissolved metal ion concentrations in the T/Dp (loading of 1 mg/L, 28 d, pH 6 and pH 8) and corresponding long-term ERVs is also well below 1 (< 0.1). Thus, the pigment does not meet classification criteria for a long-term aquatic hazard under CLP.
Two supporting non-GLP studies on the acute toxicity of the dispersed pigment on zebrafish (OECD TG 203) and Daphnia magna (OECD TG 202) provide further evidence on the low potential for aquatic toxicity since effects were not observed at 100 mg/L (nominal, dispersed) and the respective LC/EC50 values are estimated with > 100 mg/L (nominal, dispersed). Thus, applying the surrogate approach according to Table 4.1.0 (b) (iii) of Regulation (EC) No 1272/2008, tin antimony grey cassiterite would also not meet criteria for any long-term aquatic hazard category.
Thus, in accordance with Figure IV.5 „Classification strategy for determining long-term aquatic hazard for metal compounds“ of ECHA Guidance on the Application of the CLP Criteria (V 5.0, July 2017) and section 4.1.2.10.2. of Regulation (EC) No 1272/2008, classification for long-term (acute) aquatic hazard is not required for tin antimony grey cassiterite.
The conclusion on a lack of an aquatic hazard potential of tin antimony grey cassiterite is in accordance with a Tier 2 assessment (using T/Dp data) performed with MECLAS version 5.2 (http://www.meclas.eu/accessed on 10.01.2019). The Metals Classification Tool (MECLAS) is a web enabled classification tool always updated to the latest classification guidance, legal ruling, information on toxicity references and available self-classifications.
In sum, it can safely be assumed that tin antimony grey cassiterite does not meet classification criteria of an acute or long-term aquatic hazard of Regulation (EC) No 1272/2008.
Reference:
EU (European Union), 2008. European Union Risk Assessment Report. Diantimony trioxide. CAS No. 1309-64-4. EINICS No. 215-175-0, November 2008). Available from https://echa.europa.eu/documents/10162/553c71a9-5b5c-488b-9666-adc3af5cdf5f
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
