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Diss Factsheets
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EC number: 234-201-1 | CAS number: 10595-06-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- The study is performed according to GLP and following OECD Guideline 301D, with no reported deviations. A 250 mg/l stock solution of the test substance could not be made, instead a 50 mg/l was prepared, this is beleived not to affect the results of the study.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 D (Ready Biodegradability: Closed Bottle Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- sewage, domestic, non-adapted
- Details on inoculum:
- Secondary effluent collected at municipal waste water treatment plant, which primarily receives domestic sewage.
- Duration of test (contact time):
- 28 d
- Initial conc.:
- 2.5 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- test was run with test medium alone (inoculum control), test medium with test substance (test suspension), test medium with reference substance (activity control) and test medium with test and reference substance (toxicity control).
- Reference substance:
- benzoic acid, sodium salt
- Parameter:
- % degradation (O2 consumption)
- Value:
- 22.3
- Sampling time:
- 28 d
- Results with reference substance:
- The biodegradation of the reference substance sodium benzoate was 73.0% in 28 days, therefore the test can be considered valid.
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- inherently biodegradable, fulfilling specific criteria
- Conclusions:
- The tested substance 2-phenoxyethyl acrylate cannot be considered readily biodegradable, on the basis of the results, as biodegradation of 22.3 % was observed in 28 days.
- Executive summary:
A OECD Guideline study 301D was performed on 2 -phenoxyethyl acrylate according to GLP. The substance demonstrated a biodegradation of 22.3 % in 28 days, and can therefore not be considered readily biodegradable, as criteria for readily biodegradation is 60% in 28 days.
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Justification for type of information:
- Read-across from a OECD 301 study on one closely structural and physicochemical related substance: 2-Phenoxyethyl acrylate (M140).
For further read-across justification se document attached in section 13. - Reason / purpose for cross-reference:
- read-across source
- Reason / purpose for cross-reference:
- read-across source
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- 22.3
- Sampling time:
- 28 d
- Validity criteria fulfilled:
- not applicable
- Interpretation of results:
- inherently biodegradable
- Conclusions:
- No data is available for 2-Phenoxyethyl methacrylate (T).
Biodegradation in water was performed on 2-phenoxyethyl acrylate in accordance with OECD Guideline study 301D. The substance demonstrated a biodegradation of 22.3 % in 28 days, and cannot be considered readily biodegradable, as criteria for readily biodegradation is 60% in 28 days.Based on read-across to other acrylates it was however concluded that 2-phenoxyethyl acrylate is at least inherently biodegradable.
Due to structural and physico-chemical similarity to 2-Phenoxyethyl acrylate, it can also be concluded for 2-Phenoxyethyl methacrylate that it is inherently biodegradable as well. - Executive summary:
No data is available for 2-Phenoxyethyl methacrylate (T).
Biodegradation in water was performed on 2-phenoxyethyl acrylate in accordance with OECD Guideline study 301D. The substance demonstrated a biodegradation of 22.3 % in 28 days, and cannot be considered readily biodegradable, as criteria for readily biodegradation is 60% in 28 days. Based on read-across to other acrylates it was concluded that
2-phenoxyethyl acrylate is at least inherently biodegradable.
Due to structural and physico-chemical similarity to 2-Phenoxyethyl acrylate, it can also be concluded for 2-Phenoxyethyl methacrylate that it is inherently biodegradable.
See justification for read-across attached in section 13.
- Endpoint:
- biodegradation in water: inherent biodegradability
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: QSAR based on good data for several substances in family
- Justification for type of information:
- QSAR based on data for several acrylates
- Principles of method if other than guideline:
- Read-across from other substances with structure similar to structure of test substance
- GLP compliance:
- yes
- Remarks:
- Assumed to be performed in accordance to GLP
- Specific details on test material used for the study:
- Details on properties of test surrogate or analogue material:not relevant
- Oxygen conditions:
- not specified
- Inoculum or test system:
- not specified
- Details on inoculum:
- not relevant
- Preliminary study:
- Read-across to results from ready-biodegradabilty studies (OECD 301) for other similar substances showed that the test substance is most likely to be ready biodegradable. EpiSuite calculations support this. However, as the conclusion from ready-biodegradability test was that the substance is not readily biodegradable, it was assessed that a conservative conclusion from the read-across study is that the test substance is very likely to be at least inherently biodegradable.
- Test performance:
- Read-across
- Remarks on result:
- other: Not relevant, read-across
- Details on results:
- Read-across, so no %degradation is specified.
- Results with reference substance:
- not relevant
- Validity criteria fulfilled:
- not specified
- Interpretation of results:
- inherently biodegradable
- Conclusions:
- Based on the Read-across assessment the substance is concluded to be inherently biodegradable.
- Executive summary:
Read-across to results from ready-biodegradabilty studies (OECD 301) for other similar substances showed that the test substance is most likely to be readily biodegradable. EpiSuite calculations support this. However, as the conclusion from ready-biodegradability test was that the substance is not readily biodegradable, it was assessed that a conservative conclusion from the read-across study is that the test substance is very likely to be at least inherently biodegradable.
Referenceopen allclose all
Description of key information
No data is available for 2-Phenoxyethyl methacrylate (T).
Biodegradation in water was performed on 2-phenoxyethyl acrylate (S) in accordance with OECD Guideline study 301D. The substance demonstrated a biodegradation of 22.3 % in 28 days, and cannot be considered readily biodegradable, as criteria for readily biodegradation is 60% in 28 days.
Due to structural and pysico-chemical similarity to 2-Phenoxyethyl methacrylate, a biodegradation of 22.3 % in 28 days meaning that it is not readily biodegradable can also be concluded for 2-Phenoxyethyl methacrylate as well.
Key value for chemical safety assessment
- Biodegradation in water:
- inherently biodegradable, fulfilling specific criteria
Additional information
The pass-criteria for readily biodegradability test was not full-filled in the readily biodegradability test of 2-phenoxyethyl acrylate (S).However, read-across to other substances with similar structures and EpiSuite calculations strongly supports that 2-phenoxyethyl acrylate (S) should at least be inherently biodegradable, fulfilling specific criteria.
Due to structural and physico-chemical similarity to 2-Phenoxyethyl methacrylate, the same can also be concluded for 2 -Phenoxyethyl methacrylate as well.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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