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EC number: 627-023-4 | CAS number: 2441-41-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2008-12-09 to 2009-01-27
- Reliability:
- 1 (reliable without restriction)
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- Deviations:
- yes
- Remarks:
- A deviation to the study plan n°08/1124F was observed in this study: soda lime pellets were used instead of potassium hydroxyde pellets. There is no consequence on the results of this study
- GLP compliance:
- yes
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, adapted
- Details on inoculum:
- Sample Site: Water treatment plant "Louis Fargue", Bordeaux (France)
Date of sampling : 200-12-09
Physico-chemical characteristic of inoculum:
Suspend solid: 2.4 g/L
pH: 7.1
Dissolved oxygen: 6.7mg/L
Activated sludge preparation:
- Filtration through a 5 mm sieve
- 3 successives decantations into mineral medium
- activated sludge aeration during 7 days
- Duration of test (contact time):
- ca. 28 d
- Initial conc.:
- 100 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- Incolum control: Only inoculum
Reference item : Sodium benzoate 60.7 mg/L + inoculum
Toxicity control : test item 100mg/L + sodium benzoate 60.7 mg/L + inoculum
test item : 100 mg/L + inoculum
Study duration: 28 days
Light intensity: Darkness
Test temperature: 20°C +/- 1°C
Mineral medium composition (batch 7/15120801
Na2HPO4, 2H2o : 334 mg/L
K2HPO4 : 217.5 mg/L
NH4Cl : 5 mg/L
KH2PO4 : 85 mg/L
CaCl2, 2H2O : 36.4 mg/L
MgSO4, 7H2O : 22.5 mg/L
FeCL3, 6H2O : 0.25 mg/L
- Reference substance:
- benzoic acid, sodium salt
- Test performance:
- All validity criteria given by the OECD 301F guidelines were respected:
- Oxygen uptake of the inoculum control was not greater than 60 mg/L
- Variation between the two test item replicates was inferior to 20% at the end of the test.
- Reference item showed a biodegradability superior to 60% within 4 days
- Toxicity controls biodegradation was superior to 25% with 14 days
- pH values were comprised between 6 and 8.5.
- Parameter:
- % degradation (O2 consumption)
- Value:
- 45.27
- Sampling time:
- 10 d
- Remarks on result:
- other: without nitrification correction
- Parameter:
- % degradation (O2 consumption)
- Value:
- 78.6
- Sampling time:
- 28 d
- Remarks on result:
- other: without nitrification correction
- Parameter:
- % degradation (O2 consumption)
- Value:
- 69.8
- Sampling time:
- 28 d
- Remarks on result:
- other: With nitrification correction
- Details on results:
- No test item analysis in test item solutions has been made. However, nitrates and nitrites concentrations were determined at the start and the end of the study in the flask containing only test item.
Nitrate concentration (mg/L):
- T0: 1.15
- T28d: 17.6
Nitrate concentration (mg/L):
- T0 <0,01
- T28d: <0.01 - Results with reference substance:
- Reference Item showed a biodegradability superior to 60% within 4 days
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable, but failing 10-day window
- Conclusions:
- Considering biodegradability with nitrification correction and the 60% pass level not reached in a 10 days window, the test item 1680JG canot be considered as a readily biodegradable substance.
- Executive summary:
Ready biodegradability of the test item 1680JG was performed according to the OECD 301F guideline. The results obtained show that, without nitrification correction, the test item biodegradation reached 78.6% at the end of the study (i.e. 28days), the 60% pass level was almost reached in a 10 days window.
Howaver, as the test item contains N, a correction for oxygen uptake for interference by nitrification was needed. Considering biodegradability with nitrification correction and the 60% pass level not reached in a 10 days window, the test item 1680JG canot be considered as a readily biodegradable substance.
Reference
Description of key information
A ready biodegradability test of the substance was performed according to the OECD 301 F guidline.The results obtained show that, without nitrification corection, the test item biodegradation reached 78.6% at the end of the study(i.e.28 days), the 60% pass level was almost reached in a 10 days window.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
- Type of water:
- freshwater
Additional information
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