Calcium hydrogen phosphonate

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

08-22-2016 to 12-13-2016

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

GLP compliance:

yes (incl. QA statement)

Type of method:

flask method

Key result

Water solubility:

246.2 mg/L

Conc. based on:

test mat.

Temp.:

19.9 °C

pH:

>= 6.5 - <= 7

Details on results:

Definitive test :

No significant differences were found between filtered or centrifuged samples. As a consequence, all samples were used to determine the water solubility limit.

The saturation equilibrium was considered to be reached from the first sampling time T24h as the concentrations measured in all vessels did not differ by more than 15% during all the sampling period. The water solubility of this substance was therefore calculated as the mean of the concentrations, the value obtained was 246.2 mg/L.

The temperature in the test system was monitored during the test, it was remained between 19.8°C and 20.2°C throughout the experiment (mean 19.9°C).

In all control and test item samples, pH were ranged from 6.5 to 7.0.

Preliminary test :

1 mL of ultra-pure water were necessary to dissolve 0.5 mL of test item, but solutions obtained were not homogenous and appeared "milky".

A flask test was nevertheless decided in accordance to the study monitor.

Conclusions:

Validity criteria fulfiiled : the saturation equilibrium was considered to be reached from the first sampling time T24h as the concentrations measured in all vessels did not differ by more than 15% during all the sampling period.

The water solubility of the test item Calcium hydrogenophosphonate was assessed according to the OECD 105 guideline.
the water solubility of Calcium hydrogenophosphonate is 246.2 mg/L.

Executive summary:

The water solubility of Calcium hydrogenophosphonate was determined according to the OECD 105 guideline (flask method).

 

Results are summarized hereafter for hydrogenophosphate:

 

Sampling time (h after T0)	Mean of all samples	Difference*	Overall Mean Measured Test Item(mg/L)*
24h	164.8	NA	164.1
48h	161.7	-1.9%
72h	167.2	3.4%

 

The solubility of Calcium hydrogenophosphonate (164.1 * 1.5 to take calcium into account) is 246.2 mg/L.

 

The test was run at 19.9°C and the pH ranged from 6.5 to 7.0.

Description of key information

The water solubility of Calcium hydrogenophosphonate was determined according to the OECD 105 guideline (flask method).

 

Results are summarized hereafter for hydrogenophosphate:

 

Sampling time (h after T0)	Mean of all samples	Difference*	Overall Mean Measured Test Item(mg/L)*
24h	164.8	NA	164.1
48h	161.7	-1.9%
72h	167.2	3.4%

 

The solubility of Calcium hydrogenophosphonate (164.1 * 1.5 to take into calcium into account) is 246.2 mg/L.

 

The test was run at 19.9°C and the pH ranged from 6.5 to 7.0.

Key value for chemical safety assessment

Water solubility:

246.2 mg/L

at the temperature of:

19.9 °C