Registration Dossier
Registration Dossier
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EC number: 277-179-9 | CAS number: 72987-16-7
Endpoint summary
Administrative data
Description of key information
Skin: in a human test, the test item was applied through textile as pure substance and mixed with water and peanut oil, respectively. No irritation effects related to the substance occured. The weak irritation signs (redness) that were fully reversible within the observation period (11 d) also occurred in the negative controls (textile only without test item). Therefore, they were considered mechanic but not substance-related effects. No signs of corrosion or edema occurred.
Eye: no signs of eye irritation occurred in two OECD 405 in vivo studies (rabbit). Unsignificant chemosis occured after application but was fully reversible within 48 h.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Respiratory irritation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
Justification for classification or non-classification
No signs (skin/eye) of irritation occurred in the in vivo studies (humans, rabbits). Therefore, the substance is not classifiable.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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