Registration Dossier
Registration Dossier
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EC number: 251-311-5 | CAS number: 32961-44-7
Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 016
- Report date:
- 2016
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
- Deviations:
- no
- GLP compliance:
- no
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
Test material
- Reference substance name:
- Isobutyl 4-chloro-3,5-diaminobenzoate
- EC Number:
- 251-311-5
- EC Name:
- Isobutyl 4-chloro-3,5-diaminobenzoate
- Cas Number:
- 32961-44-7
- Molecular formula:
- C11H15ClN2O2
- IUPAC Name:
- 2-methylpropyl 3,5-diamino-4-chlorobenzoate
- Test material form:
- solid
Constituent 1
Study design
- Analytical method:
- high-performance liquid chromatography
Results and discussion
Partition coefficient
- Key result
- Type:
- log Pow
- Partition coefficient:
- -0.97
- Remarks on result:
- other: Temperature and pH were not specified in the study.
Applicant's summary and conclusion
- Conclusions:
- The log Pow of isobutyl 4-chloro-3,5-diaminobenzoate was determined to be -0.97 in a OECD 117 study (using reverse phase HPLC method) with acceptable restrictions, hence, the result for the test material can be considered as reliable.
- Executive summary:
The log Pow of isobutyl 4-chloro-3,5-diaminobenzoate was determined using reverse phase HPLC according to OECD guideline 117, with acceptable restrictions, to be -0.97.
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