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EC number: 220-476-5 | CAS number: 2778-96-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
From BCFBAF (v3.00) model of EPI suite the estimated bio concentration factor (BCF) for test chemical is 3.2 L/kg wet-wt which does not exceed the bioconcentration threshold of 2000.Thus it is concluded that test chemical is not expected to bio accumulate in the aquatic environment.
Additional information
Three results including different predicted data from validated models and experimental data from authoritative database for bioaccumulation (BCF) endpoint of target chemical Octadecyl stearate (CAS no. 2778-96-3) were summarized as follows:
First data from BCFBAF (v3.00) model of EPI suite the estimated bio concentration factor (BCF) for test chemical is 3.2 L/kg wet-wt which does not exceed the bioconcentration threshold of 2000.Thus it is concluded that test chemical is not expected to bio accumulate in the aquatic environment.
Above predicted result of target supported by experimental data of test chemical from authoritative database in this study the
BCF value of test chemical was estimated to be 3.0 dimensionless by using an estimated log Kow of 17.7 and a regression derived equation. On the basis of this estimated BCF value it can be concluded that test chemical in non bioaccumulative in nature.
Next study was also reviewed from same data source as mentioned above in this the BCF value of test chemical was estimated to be 3.0 dimesionless by using an estimated log Kow of 13.45 and a regression derived equation. On the basis of this estimated BCF value it can be concluded that test chemical in non bioaccumulative in nature and the potential for bioconcentration in aquatic organisms (fish) is low.
In another study bioaccumulation of test chemical was conducted on test organism Lepomis macrochirusfor 49 days for evaluating the bioconcentration factor (BCF value) of test chemical. Lepomis macrochirus was used as a test organism for the study. The test was conductedin aerated carbon–filtered well water and Town River water under flow-through system. The BCF after exposure in the contaminated river water was detected with BCF <5 in the filet 94 in the viscera and 13 in the whole body. After 14 days in clear water 93 % of test chemical was detected to be eliminated. It was concluded that bluegill concentrated test chemical in well water about three times more than in river water. 49 days of exposure phase followed by a depuration phase that ranged from 21–35 days. During both phases edible (filets) and inedible (visceral) tissues of 5 fish were analyzed in duplicate for both total radioactivities at least once a week. The bioconcentration factor (BCF value) of test chemicalonLepomis macrochiruswas determined to be 13 at concentration of0.023 mg/l which does not exceed the bioconcentration threshold of 2000, indicating that the test chemicalisnot expected to bioaccumulate in the food chain.
Thus based on the above information for bioaccumulation endpoint, it can be concluded that the test substance is expected to be non bioaccumulative in aquatic environment.
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