Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: - | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
![](https://echa.europa.eu/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/print_physical-and-chemical-properties.png)
Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Experimental Starting Date: 20 July 2012; Experimental Completion Date: 23 January 2013
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Study conducted to GLP and in compliance with agreed protocols, with no or minor deviations from standard test guidelines and/or minor methodological deficiencies, which do not effect the quality of the relevant results.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 013
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7840 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
Test material
- Test material form:
- other: solid
Constituent 1
Results and discussion
Water solubilityopen allclose all
- Water solubility:
- >= 99.2 g/L
- Temp.:
- 20 °C
- pH:
- 3.5
- Remarks on result:
- other: The solubility of the substituted-(naphthalen-1-methyl)heteromonocyclic chloride content of the test item was determined analytically to be equivalent to ≥99.2 g/L of solution
- Water solubility:
- 12.6 - 99 g/L
- Temp.:
- 20 °C
- pH:
- 3.5
- Remarks on result:
- other: A number of impurity peaks were also monitored and these showed varied solubility characteristics, with equivalent test item concentrations in the range 12.6 to ≥99.0 g/L of solution
Any other information on results incl. tables
Results
Preliminary Test
The preliminary estimation of the water solubility, as equivalent test item concentration (g/L) monitoring the substituted-(naphthalen-1-methyl)heteromonocyclic chloride content of the test item, and the sample solution pH, are shown in the following table:
Equivalent Test Item Concentration |
Solution pH |
≥51.1 |
3.4 |
Definitive Test
See attached background material for typical chromatography.
The mean peak areas relating to the standard and sample solutions are attached in background material. Quantification was performed using the x 200 dilution factor sample solutions, which resulted in mean peak areas most comparable to the standard solutions on analysis for a majority of the components.
The definitive test sample solution concentration, as equivalent test item concentration (g/L) monitoring the substituted-(naphthalen-1-methyl)heteromonocyclic chloride content of the test item, and the sample solution pH, are shown in the following table:
Table 3.22
Equivalent Test Item Concentration |
Solution pH |
≥99.2 |
3.5 |
The definitive test sample solution concentration of a number of impurities present in the test item, as equivalent test item concentration (g/L), and the sample solution pH are shown in the following table:
Table 3.23
Components Monitored (Retention Time |
Mean Equivalent Test Item Concentration |
Solution pH |
3.0 to 16.5[1] |
≥99.0 |
3.5 |
16.5 to 18.0 |
35.5 |
|
18.2 to 19.2 |
≥97.8 |
|
19.4 |
23.4 |
|
20.5 to 22.0 |
73.0 |
|
22.5 to 23.5 |
69.1 |
|
23.8 to 24.9 |
12.6 |
[1]Including response originating from the substituted-(naphthalen-1-methyl)heteromonocyclic chloride
content of the test item
Applicant's summary and conclusion
- Conclusions:
- Interpretation of results (migrated information): very soluble (> 10000 mg/L)
The solubility of the substituted-(naphthalen-1-methyl)heteromonocyclic chloride content of the test item was determined analytically to be equivalent to ≥99.2 g/L of solution at 20.0 ± 0.5 °C.
A number of impurity peaks were also monitored and these showed varied solubility characteristics, with equivalent test item concentrations in the range 12.6 to ≥99.0 g/L of solution at 20.0 ± 0.5 °C.
No determination of the water solubility of the propane-1,2-diol content of the test item was performed as this compound had been identified from literature references to be miscible with water. - Executive summary:
Method
The determination was carried out using a flask method, designed to address the data endpoint of Method A6 Water Solubility of Commission Regulation (EC) No 440/2008 of 30 May 2008, Method 105 of the OECD Guidelines for Testing of Chemicals, 27 July 1995, and Method 830.7840 of the OPPTS Guidelines.
Result
The solubility of the substituted-(naphthalen-1-methyl)heteromonocyclic chloride content of the test item was determined analytically to be equivalent to ≥99.2 g/L of solution at 20.0 ± 0.5 °C.
A number of impurity peaks were also monitored and these showed varied solubility characteristics, with equivalent test item concentrations in the range 12.6 to ≥99.0 g/L of solution at 20.0 ± 0.5 °C.
No determination of the water solubility of the propane-1,2-diol content of the test item was performed as this compound had been identified from literature references to be miscible with water.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
![ECHA](/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/echa_logo.png)
Bien que l'ECHA fournisse énormément de matériel en ligne dans votre langue, une partie de cette page n'est disponible qu'en anglais. De plus amples informations sur la pratique multilingue de l'ECHA sont disponibles.
Bienvenue sur le site web de l'ECHA. Ce site n'est pas entièrement compatible avec Internet Explorer 7 (ni avec les versions antérieures). Veuillez mettre à jour Internet Explorer.
Ce site web utilise des cookies afin de vous garantir la meilleure expérience possible sur nos sites web.
Pour en savoir plus sur la façon dont nous utilisons les cookies.