Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
documentation insufficient for assessment

Data source

Reference
Title:
No information
Author:
Rush G M, Bowden A M, Muijser H and Arts J (2008), Inhalation Toxicology, 20: 665-670

Materials and methods

Principles of method if other than guideline:
Two 1-h exposures on groups of 6 male rats.
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Fluorosulphuric acid
EC Number:
232-149-4
EC Name:
Fluorosulphuric acid
Cas Number:
7789-21-1
Molecular formula:
FHO3S
IUPAC Name:
sulfurofluoridic acid
Details on test material:
- Name of test material (as cited in study report): fluorosulfonic acid (FSA)
- Analytical purity: 98% pure

Administration / exposure

Duration of exposure:
ca. 1 h

Results and discussion

Any other information on results incl. tables

A concentration of 4125 mg/m3 fluorosulphuric acid resulted in a clearly decreased breathing rate during and shortly after exposure with 67% (4/6) mortality on days 5-9 after exposure. A concentration of 845 mg/m3 fluorosulphuric acid resulted in only minor signs of irritation, consisting of slight changes in breathing pattern shortly after exposure.

Applicant's summary and conclusion