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EC number: 203-055-0 | CAS number: 102-79-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- activated sludge respiration inhibition testing
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1987-03-10
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Guideline study with acceptable restrictions (source of inoculum industrial instead of domestic wwtp)
- Qualifier:
- according to guideline
- Guideline:
- ISO 8192 (Water quality - Test for inhibition of oxygen consumption by activated sludge for carbonaceous and ammonium oxidation)
- GLP compliance:
- no
- Analytical monitoring:
- no
- Vehicle:
- no
- Test organisms (species):
- activated sludge, industrial
- Details on inoculum:
- - Source: activated sludge of an wwtp treating industrial sewage (BASF AG)
- Initial biomass concentration: dry matter: 1 g/L - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 30 min
- Test temperature:
- 20-25 °C
- Nominal and measured concentrations:
- nominal: 0 (control), 363, 727 mg/L
- Reference substance (positive control):
- not specified
- Key result
- Duration:
- 30 min
- Dose descriptor:
- other: EC20
- Effect conc.:
- > 727 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- inhibition of total respiration
- Remarks:
- respiration rate
- Validity criteria fulfilled:
- yes
- Conclusions:
- EC20 > 727 mg/L (nominal concentration)
- Executive summary:
The toxicity of Butyldiethanolamine towards aquatic microorganisms was determined according to the international standard ISO 8192 (BASF, 1987). Activated sludge of an wwtp treating industrial sewage (BASF AG) with an initial biomass concentration of 1 g dw/L was exposed to the test substance for 30 minutes. Test concentrations of 0 (control), 363 and 727 mg/L were applied. Based on the respiration rate, the EC20 was determined to be > 727 mg/L (nominal concentration).
Reference
Respiration inhibition:
Test results after an incubation of 30 min:
Test concentration |
Respiration rate |
Respiration change* |
[mg/L] |
[mg O2/L/h] |
[%] |
blank |
27 |
|
363 |
36 |
-33 |
727 |
36 |
-33 |
*: negative values represent inhibition of respiration; positive values represent promotion of respiration
Description of key information
Butyldiethanolamine_ISO 8192_BASF-1987: EC20 (30 min) > 727 mg/L (nominal concentration)
Key value for chemical safety assessment
Additional information
The toxicity of the registered substance Butyldiethanolamine towards aquatic microorganisms has been experimentally determined.
In addition, a study performed with the read-across substance DBEA serves as supporting information.
The toxicity of the source substance Butyldiethanolamine towards aquatic microorganisms was determined according to the international standard ISO 8192 (BASF, 1987). Activated sludge of a wwtp treating industrial sewage (BASF AG) with an initial biomass concentration of 1 g dw/L was exposed to the test substance for 30 minutes. Test concentrations of 0 (control), 363 and 727 mg/L were applied. Based on the respiration rate, the EC20 was determined to be > 727 mg/L (nominal concentration).
Furthermore, data on its structural analogue Dibutylethanolamine (DBEA, CAS 102-81-8) is taken to evaluate this endpoint (please refer also to read-across statement attached in IUCLID Section 13).
The toxicity of the read-across substance Dibutylaminoethanol (CAS 102-81-8) towards aquatic microorganisms was determined according to OECD Guideline 209 in compliance with GLP (BASF AG, 2005). Substance concentrations of 0 (blank control) and 1000 mg/L were tested (limit test). As inoculum, domestic activated sludge was used. Microorganisms were exposed to the test substance for 30 min. As reference substance, 3,5-dichlorophenol was selected. The respective EC50 (30 min) value of 3,5-dichlorophenol was in the range of 5-30 mg/L. For the test substance, an EC20 (30 min) value of > 1000 mg/L based on the respiration rate was determined.
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