Registration Dossier
Registration Dossier
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EC number: 204-496-1 | CAS number: 121-73-3
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to microorganisms
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Data is from peer reviewed journal
- Qualifier:
- according to guideline
- Guideline:
- other: as per mentioned below
- Principles of method if other than guideline:
- Test was conducted to check the effects of 1 chloronitrobenzene on photobacterium phosphoreum for 15 min.
- GLP compliance:
- no
- Specific details on test material used for the study:
- Details on properties of test surrogate or analogue material (migrated information):
No data available - Analytical monitoring:
- not specified
- Details on sampling:
- - Concentrations: 13.1mg/l
- Vehicle:
- not specified
- Details on test solutions:
- No data available
- Test organisms (species):
- Photobacterium phosphoreum
- Details on inoculum:
- Photobacteriumphosphoreum, strain NRRL-B-11177 ( occasionally also referred to as Vibrio fischerii, strain NRRL-B-11177)
- Test type:
- not specified
- Water media type:
- not specified
- Total exposure duration:
- 15 min
- Post exposure observation period:
- No data available
- Hardness:
- No data available
- Test temperature:
- Test temp:15°C
- pH:
- pH range used is 5 to 9
- Dissolved oxygen:
- No data available
- Salinity:
- No data available
- Nominal and measured concentrations:
- No data available
- Duration:
- 15 min
- Dose descriptor:
- EC50
- Effect conc.:
- 13.1 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: Reduction in light
- Details on results:
- No data available
- Results with reference substance (positive control):
- No data available
- Reported statistics and error estimates:
- No data available
- Validity criteria fulfilled:
- not specified
- Conclusions:
- The 15min EC50 value for Photobacteriumphosphoreum, strain NRRL-B-11177 exposed to 1 chloro dinitrobenzene is 13.1mg/l.
Based on the EC50 value the substance may be classified under the category of aquatic chronic 3 - Executive summary:
Aquatic toxicity study of micro-organism to the test substance was conducted usingPhotobacteriumphosphoreum, strain NRRL-B-11177 (also referred to asVibrio fischerii, strain NRRL-B-11177).
When test bacteria was exposed to the test substance 1-chloro-3-nitrobenzene with exposure duration of 15 mins, reduction in light output was observed.
Based on which the EC50 was determined to be 13.1mg/l.
Reference
Description of key information
The 15min EC50 value for Photobacteriumphosphoreum, strain NRRL-B-11177 exposed to 1 chloro dinitrobenzene is 13.1mg/l.
Based on the EC50 value the substance may be classified under the category of aquatic chronic 3.
Key value for chemical safety assessment
- EC50 for microorganisms:
- 13.1 mg/L
Additional information
Aquatic toxicity study of micro-organism to the test substance was conducted using Photobacteriumphosphoreum, strain NRRL-B-11177 (also referred to asVibrio fischerii, strain NRRL-B-11177).
When test bacteria was exposed to the test substance 1-chloro-3-nitrobenzene with exposure duration of 15 mins, reduction in light output was observed.
Based on which the EC50 was determined to be 13.1mg/l.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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