Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 217-038-0 | CAS number: 1726-23-4
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Short-term toxicity to Daphnia: EC50 - >348.7 µg/L; NOEC - 348.7 µg/L
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 348.7 µg/L
Additional information
Acute immobilisation in Daphnia has been investigated on the registered substance itself and three structural analogues of the substance. Tests were conducted according to OECD test methods and dissolution/dispersion agents were used to increase concentration of two of the substances in the test medium. In these studies the EC50 (48h) was determined to be >100 mg/L and the NOEC was 100 mg/L. Other studies resulted in the same outcome but investigated the effects of a water accommodated fraction resulting in significantly lower levels of exposure.
In contrast with the experimental values from the tested structural analogues, QSAR estimates for the registered substance predict EC50 values ranging from 4.5 mg/L to 6 mg/L. Similar values are obtained from QSAR estimates of the three structural analogues and it is considered that modelling may not be a reasonable predictor for these substances as a result of the low water solubility of these substances.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
