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EC number: 240-005-7 | CAS number: 15876-39-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 05.10.2016 to 07.10.2016
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study
- Justification for type of information:
- Data is from experimental reports following standard testing procedures.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Principles of method if other than guideline:
- Determination of the inhibition of the mobility of daphnids using OECD guideline 202.
- GLP compliance:
- not specified
- Specific details on test material used for the study:
- - Name of test material :- Dialuminium tris[2-(2,4,5,7-tetrabromo-6-oxido-3-oxoxanthen-9-yl)benzoate]
- Molecular formula :C20H8Br4O5.2/3Al
- Molecular weight :1991.5992 g/mol
- InChl :1S/3C20H8Br4O5.2Al/c3*21-11-5-9-17(13(23)15(11)25)28-18-10(6-12(22)16(26)14(18)24)20(9)8-4-2-1-3-7(8)19(27)29-20;;/h3*1-6,25-26H;;/q;;;2*+3/p-6
- Substance type: Organic
- Physical state:Solid - Test organisms (species):
- Daphnia magna
- Details on test organisms:
- TEST ORGANISM
- Common name: water flea
- Source:University of Chemistry and Technology Prague
- Feeding during test: Without feeding - Test type:
- static
- Water media type:
- freshwater
- Total exposure duration:
- 48 h
- Test temperature:
- 20°C±1 °C
- pH:
- sample at concentration 200 mg/l:pH= 7.5 changed to pH=7.7during the test,
control 1: pH=7.6 changed to pH=7.4 during the test,
control 2: pH=7.7 didnot change during the test,
control 3 : pH=7.7 changed to pH=7.6 during the test - Dissolved oxygen:
- higher than 7.9 mg/1 both in the control and the sample
- Nominal and measured concentrations:
- Nominal :10,25,50,100,200 mg/l
- Details on test conditions:
- TEST SYSTEM
- No. of organisms per vessel:5pieces
- No. of vessels per concentration (replicates): 4
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water:The stock solution 200.0 mg/l was prepared by dissolving orange powder inreconstituted water.The stock solution was kept 5 min in ultrasonic bath.The test solutions of required concentrations were prepared by mixing the stock solution of the test sample inreconstituted test water.
OTHER TEST CONDITIONS
- Adjustment of pH:sample at concentration 200 mg/l:pH= 7.5 changed to pH=7.7during the test,
control 1: pH=7.6 changed to pH=7.4 during the test,
control 2: pH=7.7 didnot change during the test,
control 3 : pH=7.7 changed to pH=7.6 during the test
- Light intensity:darkness
TEST CONCENTRATIONS
- Test concentrations: 10,25,50,100,200 mg/l - Reference substance (positive control):
- yes
- Remarks:
- K2Cr207
- Key result
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 177.7 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Remarks on result:
- other: conf. level. (107.4-294.1) mg/l
- Results with reference substance (positive control):
- - Results with reference substance valid?
- Mortality: yes
- EC50: 0.79 mg/l
- Other: - Reported statistics and error estimates:
- EC50 was calculated using nonlinear regression by the software Prism4.0 (GraphPadSoftware, Inc.,SanDiego CA)
- Conclusions:
- The EC50 value for short term toxicity to Daphnia magna using OECD guideline 202 is 177.7 mg/l. It can be concluded from the value that the Dialuminium tris[2-(2,4,5,7-tetrabromo-6-oxido-3-oxoxanthen-9-yl)benzoate] is not toxic to the aquatic environment.
- Executive summary:
Short term toxicity to aquatic invertebrates was performed in Daphnia magna following the OECD guideline 202. The test was performed for 48 hrs at different concentrations as control(1,2,3), 10, 25, 50, 100,200 mg/l .Reference substance used is K2Cr207.
5 pieces of daphnids after breeding were used in 4 numbers of replicates of chemical.The test was perfromed at a temperature of 20°C±1°C with taking 25ml per replicate in 50ml glass vessel for 48 hrs. Calulations of EC50 was calculated using nonlinear regression by the software Prism4.0 (GraphPadSoftware, Inc., SanDiegoCA).
The EC50 value for short term toxicity to Daphnia magna using OECD guideline 202 is 177.7 mg/l. It can be concluded from the value that the Dialuminium tris[2-(2,4,5,7-tetrabromo-6-oxido-3-oxoxanthen-9-yl)benzoate] is not toxic to the aquatic environment and can be considered as "not classified" as per CLP regulation.
Reference
Sample Name |
Sample no. |
Sample Information
|
c [mg/l] |
I [%] |
48 h EC50 |
||
Control 1,2,3 |
- |
Reconstituted water
|
0 |
0 |
[mg/l] |
95% CI [mg/l] |
|
15 |
12912 |
CAS No. EC No. |
15876-39-8 240-005-7 |
10.0 25.0 50.0 100.0 200.0 |
0 5.0 25.0 28.0 55.0 |
177.7 |
107.4–294.1 |
Description of key information
The EC50 value for short term toxicity to Daphnia magna using OECD guideline 202 is 177.7 mg/l. It can be concluded from the value that the Dialuminium tris[2-(2,4,5,7-tetrabromo-6-oxido-3-oxoxanthen-9-yl)benzoate] is not toxic to the aquatic environment.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 177.7 mg/L
Additional information
Following study from experimental reports following standard testing procedures by ABITEC 2016, to conclude the toxicity extent of
Di aluminium tris [2-(2,4,5,7-tetrabromo-6-oxido-3-oxoxanthen-9-yl)benzoate] (CAS: 15876-39-8) towards aquatic invertebrate is summarized as follows:
Short term toxicity to aquatic invertebrates was performed in Daphnia magna following the OECD guideline 202. The test was performed for 48 hrs at different concentrations as control(1,2,3), 10, 25, 50, 100,200 mg/l .Reference substance used is K2Cr207.
5 pieces of daphnids after breeding were used in 4 numbers of replicates of chemical.The test was perfromed at a temperature of 20°C±1°C with taking 25ml per replicate in 50ml glass vessel for 48 hrs. Calulations of EC50 was calculated using nonlinear regression by the software Prism4.0 (GraphPadSoftware,Inc.,SanDiegoCA).
The EC50 value for short term toxicity to Daphnia magna using OECD guideline 202 is 177.7 mg/l. It can be concluded from the value that the Dialuminium tris[2-(2,4,5,7-tetrabromo-6-oxido-3-oxoxanthen-9-yl)benzoate] is not toxic to the aquatic environment and can be considered as "not classified" as per CLP regulation.
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