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Diss Factsheets
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EC number: 274-660-5 | CAS number: 70528-90-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Start of experiment: 8 January 1990; End of experiment: 22 January 1990
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study with acceptable restrictions
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- Version / remarks:
- Comparable with internationally accepted guideline - Internal CIBA method A-11
- Deviations:
- not specified
- GLP compliance:
- no
- Specific details on test material used for the study:
- Name: FAT 36091/F
Purity: 39.6 % - Analytical monitoring:
- no
- Vehicle:
- yes
- Test organisms (species):
- Danio rerio (previous name: Brachydanio rerio)
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 96 h
- Test temperature:
- 23 °C
- pH:
- 8.2-8.4
- Nominal and measured concentrations:
- Nominal concentrations: 100 / 300 and 1000 mg/L
- Reference substance (positive control):
- no
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 1 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Details on results:
- - At 100 mg/L: all 10 fishes where alive at 48 and 96 hours of exposure time.
- At 300 mg/L: all 10 fishes where alive at 48 and 96 hours of exposure time.
- At 1000 mg/L: all 10 fishes where alive at 48 and 8 fishes survived at 96 hours of exposure time. - Validity criteria fulfilled:
- yes
- Conclusions:
- The LC50 of FAT 36091/F in this fish acute toxicity test was determined to be greater than 1000 mg/L.
- Executive summary:
The acute fish toxicity test was performed according to equivalent or similar guideline as OECD 203. 10 Zebra fish were used in this test at each dose level.
Fishes were tested at these differents follwing concentrations: 100, 300 and 1000 mg/L.
- At 100 mg/L: all 10 fishes where alive at 48 and 96 hours of exposure time.
- At 300 mg/L: all 10 fishes where alive at 48 and 96 hours of exposure time.
- At 1000 mg/L: all 10 fishes where alive at 48 and 8 fishes survived at 96 hours of exposure time.
Based on the findings of the study; following conculsion was drawn;
After 48 hours exposure time:
LC0 >= 1000 mg/L
LC50 > 1000 mg/L
LC100 >1000 mg/L
After 96 hours exposure time:
LC0 >300 mg/L
LC50 > 1000 mg/L
LC100 >1000 mg/L
The LC50 of FAT 36091/F in this fish acute toxicity test was determined to be greater than 1000 mg/L.
Reference
Description of key information
Several studies were carried out to determine the acute fish toxicity. The LC50 in the key acute toxicity study in fish (Batch F), performed on zebra fish was determined to be greater than 1000 mg/l (48 and 96 hours exposure time).
Supporting studies were perfomredfor all other batches and the LC50 was found to be:
- For batch A: LC50 >450 mg/L (performed on Trout, after 48 hours exposure time).
- For batch B: LC50 is 125 mg/L (performed on Trout, after 48 hours exposure time).
- For batch C: LC50 >1000 mg/L (performed on Trout, after 48 hours exposure time using Tween 80 and Acetone as vehicle).
- For batch C: LC50 >1000 mg/L (performed on Red Killi fish, after 48 hours exposure time).
- For batch D: LC50 is 550 mg/L (performed on Trout, after 48 hours exposure time).
- For batch E: LC50 is 559.49 mg/L and 462.39 mg/L (performed on Zebra fish, after 48 hours and 96 hours exposure time respectively).
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 1 000 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.