Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 931-254-9 | CAS number: 64742-49-0
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
There is no data available for this substance. However, key and supporting data is available for the structural analogues Hydrocarbons, C6-C7, isoalkanes, cyclics, <5% n-hexane and Hexane. The data is read across to this substance based on analogue read across and a discussion and report on the read across strategy is provided as an attachment in IUCLID Section 13.
Hydrocarbons, C6-C7, isoalkanes, cyclics, <5% n-hexane presented a 96-h LL50 (mortality) for Oncorhynchus mykiss of 12 mg/L.
Hexane presented a 48-h LC50 (mortality) for Oryzias latipes of >1000 µg/mL (>1000 mg/L).
Key value for chemical safety assessment
Additional information
Two study reports were available and input as endpoint records. The studies were scientifically reliable according to Klimish (Klimish et al., 1997) scoring (Klimish 1 and 2).
The study from Shell (1994) examined the short-term toxicity of the test substance SBP 60/95 LNH (Hydrocarbons, C6-C7, isoalkanes, cyclics, <5% n-hexane) to Oncorhynchus mykiss. Groups of 7 fish were exposed to concentrations of 0, 1.8, 4, 9, 20, 45, or 100 mg/L of test substance for 96-h. Test solutions were renewed daily. Fish were observed at 3, 24, 48, 72, and 96 h after exposure. Signs of toxicity and mortality was seen at the two highest concentrations by the first observation. By the 24-h observation, signs of toxicity were seen at concentrations as low as 9 mg/L. By the end of the exposure period, all fish in the 20, 45, and 100 mg/L groups had died, and one fish in the 9 mg/L group was also dead. No mortality or toxic symptoms were seen in the 4 or 1.8 mg/L groups. The 96-h LL50 for fish is 12 mg/L.
The study from Tsuji et al. (1986) examined the short-term toxicity of n-hexane to fish. Groups of 10 fish were exposed to 988.5 µg/mL of test substance for 48 h. The exposure temperature was 10, 20, or 30°C. The fish were observed for mortality at 24 and 48 h after start of exposure. The 48-h LC50for fish exposed to n-hexane was >1000 µg/mL.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
