Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 619-057-3 | CAS number: 94667-33-1
Endpoint summary
Administrative data
Description of key information
In a study conducted in accordance with U.S.EPA Guideline 165-4 (1989), Bluegill fish (Lepomis macrochirus) was exposed to the test material, Bardac 22 with radiolabelled Didecyldimethylammonium Chloride at concentrations of 0, 59.0 µg/l (actual concentration - 93 ± 32 µg/l). 220 bluegill were tested at each concentration. The test organisms were exposed to the test material in aquaria for 28 days, with an 18 day depuration period. Fish were collected on days 4, 10, 17, 24 and 28 of the exposure and on days 3, 7, 14 and 18 of depuration. Tissues from control fish were sampled on days 0 and 28 of exposure and day 18 of depuration. On day 28 of exposure, an additional five fish were sampled and divided into three tissue portions; edible (fillets), non-edible (head, fins and viscera) and skin. Edible tissues from each of three sets of approximately 10 fish sampled on day 28 were subjected to hexane/methanol tissue extraction, combusted and then counted to quantify that portion of the14C-residue not extractable with either solvent. Five treated fish died during the exposure test and no fish died during depuration. Under the conditions of this study, for edible tissue, the BCF was 38 (predicted 52) and elimination after 14 and 18 Days was 57% and 38%, respectively. For non-edible tissue, the BCF was 140 (predicted 160) and elimination after 14 and 18 Days was 71% and 66%, respectively. For whole-body, the BCF was 81 (predicted 95) and elimination after 14 and 18 Days was 67% and 56%, respectively. In conclusion, skin tissue showed14C-residues 2 to 6 times higher than edible tissue portions. The test substance may bind significantly to skin and scales of exposed fish. Of the accumulated14C-residue in the edible tissue of bluegill exposed 28 days to the test substance, 65.5% was extractable with a polar solvent (methanol), 8.1% was extractable with a nonpolar solvent (hexane) and 25.9% was not extractable with either solvent.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
