Registration Dossier
Registration Dossier
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EC number: 431-850-4 | CAS number: 7456-68-0
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation / corrosion
- Adequacy of study:
- other information
Data source
Reference
- Reference Type:
- other: Body responsible for the test
- Title:
- Unnamed
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: 92/69/EWG, B.4
- GLP compliance:
- yes
Test animals
- Species:
- other: rbt, New Zealand White
Test system
- Type of coverage:
- semiocclusive
- Vehicle:
- other: 0.5 % Methylcellulose in Wasser "ENGLISH" 0.5 % methylcellulose in water
- Amount / concentration applied:
- 500 mg
- Duration of treatment / exposure:
- 4 h
- Number of animals:
- 6
Results and discussion
In vivo
Resultsopen allclose all
- Irritation parameter:
- erythema score
- Basis:
- mean
- Score:
- 0
- Max. score:
- 0
- Remarks on result:
- other: Max. duration: 0 d; Max. value at end of observation period: 0
- Irritation parameter:
- edema score
- Basis:
- mean
- Score:
- 0
- Max. score:
- 0
- Remarks on result:
- other: Max. duration: 0 d; Max. value at end of observation period: 0
- Other effects:
- Bei einem Kaninchen mit klarem, schleimigem Kot wurde nach
48 und 72 Stunden Ausfluss von Kot festgestellt.
"ENGLISH"
One rabbit was observed with clear, mucous appearing feces
and fecal soiling at 48hr and 72 hr, however, this was
considered not to be treatment related.
Applicant's summary and conclusion
- Interpretation of results:
- other: not classified
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