Rosin

GHS

General Information

Implementation:

EU

Remarks:

Annex VI, CLP Reg - CAS #: 8050-09-7
Remarks: No evidence of a sensitization response was observed in the key study, a guideline Local Lymph Node Assay conducted in mice, or in ten supporting studies conducted in guinea pigs according to the GPMT or Buehler methods. Gum Rosin is not classified for dermal sensitization according to the UN Globally Harmonized System of Classification and Labelling of Chemicals (GHS). Gum Rosin is currently classified for Skin Sensitization according to Annex I to Directive 67/548/EEC as R43: May cause sensitization by skin contact. Gum Rosin is also classified according to EU Classification, Labelling and Packaging of Substances and Mixtures (CLP) Regulation (EC) No. 1272/2008. As part of the harmonized translation between Directive 67/548/EEC and EU CLP Regulation (EC) No. 1272/2008, Table 3.1 of EU CLP Regulation (EC) No. 1272/2008 classifies Gum Rosin as “Skin Sensitizer Category 1” and assigns the hazard statement H317: May cause an allergic skin reaction. Table 3.2 of EU CLP Regulation (EC) No. 1272/2008 contains a list of harmonized classifications and labelling of hazardous substances from Annex I to Directive 67/548/EEC. Gum Rosin is assigned the risk phrase R43: May cause sensitization by skin contact in Table 3.2.

Subsequent evaluation determined that the single positive study for Gum Rosin was actually conducted with an oxidized form of the test material. Several esters of Rosin have been tested using similar protocols with similar results. When the Rosin esters were heated beyond the specified protocol, the oxidized material caused a positive sensitization response. When those same esters were retested using a different protocol which did not cause oxidation, all sensitization responses were negative. While the oxidized form of Gum Rosin should be considered a skin sensitizer, the recommendation is made to declassify non-oxidized Gum Rosin (CAS # 8050-09-7).

Classification

Physical hazards

Explosives

Reason for no classification:

data conclusive but not sufficient for classification

Flammable gases and chemically unstable gases

Reason for no classification:

data conclusive but not sufficient for classification

Aerosols

Reason for no classification:

data conclusive but not sufficient for classification

Reason for no classification:

hazard class not assessed

Oxidising gases

Reason for no classification:

data conclusive but not sufficient for classification

Gases under pressure

Reason for no classification:

data conclusive but not sufficient for classification

Flammable liquids

Reason for no classification:

data conclusive but not sufficient for classification

Flammable solids

Reason for no classification:

data conclusive but not sufficient for classification

Self-reactive substances and mixtures

Reason for no classification:

data conclusive but not sufficient for classification

Pyrophoric liquids

Reason for no classification:

data conclusive but not sufficient for classification

Pyrophoric solids

Reason for no classification:

data conclusive but not sufficient for classification

Self-heating substances and mixtures

Reason for no classification:

data conclusive but not sufficient for classification

Substances and mixtures which in contact with water emit flammable gases

Reason for no classification:

data conclusive but not sufficient for classification

Oxidising liquids

Reason for no classification:

data conclusive but not sufficient for classification

Oxidising solids

Reason for no classification:

data conclusive but not sufficient for classification

Organic peroxides

Reason for no classification:

data conclusive but not sufficient for classification

Corrosive to metals

Reason for no classification:

data conclusive but not sufficient for classification

Desensitized explosives

Reason for no classification:

data lacking

Health hazards

Acute toxicity - oral

Reason for no classification:

data conclusive but not sufficient for classification

Acute toxicity - dermal

Reason for no classification:

data conclusive but not sufficient for classification

Acute toxicity - inhalation

Reason for no classification:

data conclusive but not sufficient for classification

Skin corrosion / irritation

Reason for no classification:

data conclusive but not sufficient for classification

Serious eye damage / eye irritation

Reason for no classification:

data conclusive but not sufficient for classification

Respiratory sensitisation

Reason for no classification:

data conclusive but not sufficient for classification

Skin sensitisation

Hazard category:

Skin Sens. 1

Hazard statement:

H317: May cause an allergic skin reaction.

Aspiration hazard

Reason for no classification:

data conclusive but not sufficient for classification

Reproductive toxicity

Reason for no classification:

data conclusive but not sufficient for classification

Effects on or via lactation

Reason for no classification:

data conclusive but not sufficient for classification

Germ cell mutagenicity

Reason for no classification:

data conclusive but not sufficient for classification

Carcinogenicity

Reason for no classification:

data conclusive but not sufficient for classification

1. Specific target organ toxicity - single (STOT-SE)

Reason for no classification:

data conclusive but not sufficient for classification

1. Specific target organ toxicity - repeated (STOT-RE)

Reason for no classification:

data conclusive but not sufficient for classification

Environmental hazards

Hazardous to the aquatic environment (acute / short-term)

Reason for no classification:

data conclusive but not sufficient for classification

Hazardous to the aquatic environment (long-term)

Reason for no classification:

data conclusive but not sufficient for classification

Hazardous to the ozone layer

Reason for no classification:

data conclusive but not sufficient for classification

Labelling

Signal word:

Warning

Hazard pictogram

GHS07: exclamation mark

Hazard statements

H317: May cause an allergic skin reaction.

Precautionary statements

P261: Avoid breathing dust/fume/gas/mist/vapours/spray.

P280: Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

P302+P352: IF ON SKIN: Wash with plenty of water/…

P333+P313: If skin irritation or rash occurs: Get medical advice/attention.

P363: Wash contaminated clothing before reuse.

P501: Dispose of contents/container to ...

(hazardous waste bin)