Registration Dossier
Registration Dossier
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EC number: 200-835-2 | CAS number: 75-05-8
Sediment toxicity
Administrative data
Link to relevant study record(s)
- Endpoint:
- sediment toxicity: short-term
- Type of information:
- experimental study
- Adequacy of study:
- disregarded due to major methodological deficiencies
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- documentation insufficient for assessment
- Principles of method if other than guideline:
- No information available
- GLP compliance:
- not specified
- Analytical monitoring:
- not specified
- Test organisms (species):
- Hyalella azteca
- Details on test organisms:
- TEST ORGANISM
- Common name: Scud - Study type:
- laboratory study
- Test type:
- not specified
- Water media type:
- not specified
- Type of sediment:
- not specified
- Test temperature:
- 23 degree C.
- Details on test conditions:
- The test was conducted using juveniles with 14-16 antenna segments.
- Duration:
- 18 h
- Dose descriptor:
- EC50
- Effect conc.:
- 6 530 mg/L
- Executive summary:
Bowman et al (1981) reported an 18-hour EC50 value of 6530 mg/L for acetonitrile in Scud, (Hyalella azteca).
- Endpoint:
- sediment toxicity: long-term
- Data waiving:
- other justification
- Justification for data waiving:
- other:
Referenceopen allclose all
Description of key information
According to the Integrated Testing Strategy for toxicity to sediment dwelling organisms (Guidance on Information Requirements and Chemical Safety Assessment, chapter 7b, figure 7.8.8) no sediment testing is necessary for a substance with a log Kow <3. Further testing on the toxicity of acetonitrile to sediment organisms is therefore not justified, and the partitioning method can be adequately used to predict the PNEC for the sediment compartment. Bowman et al (1981) reported an 18-hour EC50 value of 6530 mg/L for acetonitrile in Hyalella azteca (Scud), however due to limited information being available on the study, this data is not considered reliable and is therefore disregarded.
Key value for chemical safety assessment
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
