Registration Dossier
Registration Dossier
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EC number: 215-524-7 | CAS number: 1328-53-6 This substance is identified in the Colour Index by Colour Index Constitution Number, C.I. 74260.
Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
Description of key information
Acumulation in aquatic organisms does not expected.
Key value for chemical safety assessment
Additional information
Based on its structure and its physico-chemical properties a transportation of the substance through biological membranes can be excluded. Therefore, its bioaccumulative potential can be stated as very low and further testing is not proposed according to Annex IX, column 2, point 9.3.3.
This assumption is supported by the experimental data from tthe substance. The study was performed according to OECD 305C with Cyprinus carpio as test species. Test organisms were exposed to different concentrations of the substances for 6 weeks in a flow-through system. The test organisms were exposed to 0.1 mg/l and 0.01 mg/l of the test item. The BCFs were determined being in the range between 0.51 and 74 L/kg (NITE, J-CHECK, 1992). The solubility of the test substance in octanol and in water is extremely low. However,based on solubility ratio, the Log Kow was calculated for the CAS 1328-53-6 being in the range between -0.8 and -0.4. Therefore, bioaccumulation of the substances is not expected.
Based on the substances's structure and its physico-chemical properties and the availeble experimental data, it can be concluded that acumulation of CAS 1328 -53 -6 in aquatic organisms does not expected.
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