Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 247-569-3 | CAS number: 26266-58-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
No toxic effects up to the limit of water solubility for Oryzias latipes (Circular on Test Methods of New Chemical Substances (Japan), Fish acute toxicity test); read-across
Key value for chemical safety assessment
Additional information
No studies are available on the toxicity of Anhydro-D-glucitol trioleate (CAS No. 26266-58-0) to fish. The assessment was, therefore, based on studies conducted with the structurally similar category members Sorbitan stearate (CAS No. 1338-41-6) and Sorbitan, (Z)-9-octadecenoate (2:3) (CAS No.8007-43-0). This read across approach is in accordance with Regulation (EC) No 1907/2006, Annex XI, 1.5. Grouping of substance and read across approach. Anhydro-D-glucitol trioleate and Sorbitan, (Z)-9-octadecenoate (2:3) are both Sorbitan esters of unsaturated C18 fatty acids. Anhydro-D-glucitol trioleate mostly consists of triesters and Sorbitan, (Z)-9-octadecenoate (2:3) of di- and triesters. Since the bioavailability of diesters is expected to be higher, due to smaller molecule size, Sorbitan, (Z)-9-octadecenoate (2:3) can be considered a worst case read-across for anhydro-D-glucitol trioleate. The second read-across substance Sorbitan stearate also consists of Sorbitan esters of C18 fatty acids, but saturated. However, the substances are expected to have similar behaviour, based on data available on solubility, ready biodegradability and toxicity to aquatic organisms. Sorbitan stearate can also be seen as a worst case read-across, due to the smaller molecular size, potentially leading to better bioavailability.
The key study conducted with Sorbitan stearate (CAS No.1338-41-6) was performed as a limit test, according to the Circular on Test Methods of New Chemical Substances (Japan), in a semi-static system, using Oryzias latipes as test organism (Ministry of the Environment, Japan, 2005). The fish were exposed to the nominal test concentration of 1000 mg/L, prepared as water accommodated fractions (WAF). No mortalities were observed at the test concentration, during the 96-hour test period, and the LL50 was determined to be > 1000 mg/L. The reported measured value LC50 > 13.7 mg/L is far above the solubility of the test substance and is therefore questionable. Since additionally the substance is an UVCB and the test was performed as WAF, the nominal loading rate was considered more appropriate to be used for the assessment.
The saltwater key study conducted with Sorbitan, (Z)-9-octadecenoate (2:3) (CAS No. 8007-43-0) was performed as a according to the OECD Guideline 203 and GLP (Hudson, 2003). The marine fish Scophthalmus maximus was used as test organism. The fish were exposed to the nominal test concentration of 1000, 1800 and 3200 mg/L, prepared as water accommodated fractions (WAF). No mortalities were observed at any of the test concentrations, during the 96-hour test period, and a LC50 of > 3200 mg/L was reported.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.