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Diss Factsheets
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EC number: 930-947-3 | CAS number: 146987-98-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Bioaccumulation: aquatic / sediment
Administrative data
- Endpoint:
- bioaccumulation: aquatic / sediment
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: no information available whether the calculation model is validated for the substance under investigation
Data source
Reference
- Reference Type:
- other: unpublished calculation
- Title:
- Unnamed
- Year:
- 2 009
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Fatty acids, coco, reaction products with N,N-dimethyl-1,3-propanediamine represent a mixture containing C8-, C10-, C12-, C14-, C16-, and C18-alkyl side chains. Based on this and the variable composition of the compound (alkyl chain distribution dependent on origin of the coco fatty acid) the calculation of physico-chemical properties for the mixture is not feasible. To get a hint on the physico-chemical data, a calculation was conducted for the C8, C12 (with 40-60 percentages in a substance) and the C18 derivates. The bioconcentration factors BCF of the C8, C12 and C18 derivates were calculated using EPIWIN v4.0, BCFBAF v3.00.
- GLP compliance:
- no
Test material
- Reference substance name:
- Amides, C8-18 even numbered, N-[3-(dimethylamino)propyl]
- EC Number:
- 930-947-3
- Cas Number:
- 146987-98-6
- Molecular formula:
- R-CO(NH)(CH2)(CH2)(CH2)N(Me2), whereas R=C8-18 (even numbered)
- IUPAC Name:
- Amides, C8-18 even numbered, N-[3-(dimethylamino)propyl]
Constituent 1
- Radiolabelling:
- no
Study design
- Test type:
- other: calculation
Test conditions
- Details on estimation of bioconcentration:
- BASIS FOR CALCULATION OF BCF
- Estimation software: EPIWIN v4.0, BCFBAF v3.00
- Result based on calculated log Pow of: C8 derivate: log Kow = 2.44, C12 derivate: log Kow=4.4 and C18 derivate: log Kow = 7.35 (at 25 °C each)
Results and discussion
Bioaccumulation factoropen allclose all
- Type:
- BCF
- Value:
- 6
- Remarks on result:
- other: C8 derivate (Arnot-Gobas method)
- Type:
- BCF
- Value:
- 27
- Remarks on result:
- other: C 12 derivate (Arnot-Gobas method)
- Type:
- BCF
- Value:
- 32
- Remarks on result:
- other: C18 derivate (Arnot-Gobas method)
Any other information on results incl. tables
Fatty acids, coco, reaction products with N,N-dimethyl-1,3-propanediamine represent a mixture containing C8-, C10-, C12-, C14-, C16-, and C18-alkyl side chains. Based on this and the variable composition of the compound (alkyl chain distribution dependent on origin of the coco fatty acid) the calculation of physico-chemical properties for the mixture is not feasible. To get a hint on the physico-chemical data, a calculation was conducted for the C8, C12 (with 40-60 percentages in a substance) and the C18 derivates. Bioconcentration factors BCF of 6 (C8 derivate), 27 (C12 derivate); 32 (C18 derivate) according to Arnot-Gobas method and BCF of 18.88 L/kg wet-wt (C8 derivate), 15.77 L/kg wet-wt (C12 derivate), 2271 L/kg wet-wt (C18 derivate) according to regression-based method were calculated using EPIWIN v4.0, BCFBAF v3.00. Based on the results, it is to be expected that the C8 and C12 derivate have a very low and the C18 derivate a high potential for bioaccumulation. Due to missing information about the applicability of the calculation model in respect to the substance under investigation the results and the conclusions thereof should be treated with care.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not applicable
- Conclusions:
- Fatty acids, coco, reaction products with N,N-dimethyl-1,3-propanediamine represent a mixture containing C8-, C10-, C12-, C14-, C16-, and C18-alkyl side chains. Based on this and the variable composition of the compound (alkyl chain distribution dependent on origin of the coco fatty acid) the calculation of physico-chemical properties for the mixture is not feasible. To get a hint on the physico-chemical data, a calculation was conducted for the C8, C12 (with 40-60 percentages in a substance) and the C18 derivates. Bioconcentration factors BCF of 6 (C8 derivate), 27 (C12 derivate); 32 (C18 derivate) according to Arnot-Gobas method and BCF of 18.88 L/kg wet-wt (C8 derivate), 15.77 L/kg wet-wt (C12 derivate), 2271 L/kg wet-wt (C18 derivate) according to regression-based method were calculated using EPIWIN v4.0, BCFBAF v3.00. Based on the results, it is to be expected that the C8 and C12 derivate have a very low and the C18 derivate a high potential for bioaccumulation. Due to missing information about the applicability of the calculation model in respect to the substance under investigation the results and the conclusions thereof should be treated with care.
- Executive summary:
Fatty acids, coco, reaction products with N,N-dimethyl-1,3-propanediamine represent a mixture containing C8-, C10-, C12-, C14-, C16-, and C18-alkyl side chains. Based on this and the variable composition of the compound (alkyl chain distribution dependent on origin of the coco fatty acid) the calculation of physico-chemical properties for the mixture is not feasible. To get a hint on the physico-chemical data, a calculation was conducted for the C8, C12 (with 40-60 percentages in a substance) and the C18 derivates. Bioconcentration factors BCF of 6 (C8 derivate), 27 (C12 derivate); 32 (C18 derivate) according to Arnot-Gobas method and BCF of 18.88 L/kg wet-wt (C8 derivate), 15.77 L/kg wet-wt (C12 derivate), 2271 L/kg wet-wt (C18 derivate) according to regression-based method were calculated using EPIWIN v4.0, BCFBAF v3.00. Based on the results, it is to be expected that the C8 and C12 derivate have a very low and the C18 derivate a high potential for bioaccumulation. Due to missing information about the applicability of the calculation model in respect to the substance under investigation the results and the conclusions thereof should be treated with care.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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