Registration Dossier
Registration Dossier
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EC number: 203-745-1 | CAS number: 110-19-0
Endpoint summary
Administrative data
Description of key information
Additional information
Short-term toxicity to fish:
Medaka (Oryzias latipes): 96-h LC50 = 17 mg/L (OECD TG 203; CERI, 2000)
Long-term toxicity to fish:
In accordance with column 2 of REACH Annex IX, long-term testing shall be proposed by the registrant if the chemical safety assessment according to Annex I indicates the need to investigate further the effects on aquatic organisms. CSA resulted in RCRs below 1 for all environmental compartments, thus demonstrating safe use. Furthermore, the substance is not classified as dangerous to the environment according to Directive 67/548/EEC or Regulation (EC) No 1272/2008. Chronic toxicity is not expected based on the results of ECOSAR (NOEC > 1 mg/L; ECT, 2009). Therefore and for reasons of animal welfare a long-term toxicity study with fish is not proposed.
Short-term toxicity to aquatic invertebrates:
Water flea (Daphnia magna
): 48 -h EC50 = 25 mg/L (OECD 202; CERI, 2000)
Long-term toxicity to aquatic invertebrates:
Water flea (Daphnia magna ): 21 -d NOEC = 23 mg/L (OECD 211; CERI, 2000)
Chronic toxicity is not expected.
Growth inhibition to aquatic algae:
Pseudokirchneriella subcapitata: 72 -h NOEC: 196 mg/L, 72 -h ErC50 = 397 mg/L (OECD 201; CERI, 2000)
Toxicity to microorganisms:
Pseudomonas putida: 16 -h TTC: 200 mg/L (Growth inhibition test acc. to Bringmann & Kühn, 1980; Bringmann & Kühn, 1976/1978/1980)
The inhibition of the degradation activity of activated sludge is not anticipated when introduced in appropriately low concentrations.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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