Registration Dossier
Registration Dossier
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EC number: 246-278-9 | CAS number: 24468-13-1
PBT assessment
Administrative data
PBT assessment: overall result
- PBT status:
- the substance is not PBT / vPvB
- Justification:
The parent compound 2-ethylhexyl chloroformate (CAS 24468-13-1) rapidly hydrolyzes (DT50 = 30.2 min at pH 7 and 25°C, OECD TG 111; SafePharm, 2003) and decomposes in water into the main products 2-ethylhexanol (CAS 104-76-7) and HCl (CAS 7647-01-0). Since the PBT/vPvB criteria do not apply to inorganic substances, HCl is not assessed with regard to PBT/vPvB properties; therefore, the PBT/vPvB assessment is mainly based on data for the organic hydrolysis product 2-ethylhexanol (CAS 104-76-7).
Since 2-ethylhexanol is readily biodegradable (according to OECD criteria) it can be regarded as not P/vP. The log Kow < 3 (see IUCLID chapter 4.7) indicates no potential for bioaccumulation (not B/vB).
Due to the rapid hydrolysis of the parent compound 2-ethylhexyl chloroformate and in absence of chronic toxicity data for the compound itself, the assessment of T properties is based on the hydrolysis product 2-ethylhexanol. 2-ethylhexanol is not T since the lowest available chronic value is greater than 0.01 mg/L (algae: 72-h ErC10 = 5.3 mg/L; Huels, 1991).
In conclusion, the parent compound 2-ethylhexyl chloroformate (CAS 24468-13-1) is considered to be neither PBT nor vPvB, based on the available data for the hydrolysis product 2-ethylhexanol (CAS 104-76-7).
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