Registration Dossier
Registration Dossier
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EC number: 204-435-9 | CAS number: 120-92-3
Toxicity to terrestrial plants
Administrative data
- Endpoint:
- toxicity to terrestrial plants, other
- Remarks:
- Lactuca sativa
- Type of information:
- experimental study
- Adequacy of study:
- disregarded due to major methodological deficiencies
- Study period:
- no data
- Reliability:
- 3 (not reliable)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- The method was not completely described : no information was available about the test design. The test conditions presented in this study were not in accordance with standardized method : - the support used was agar, - the test duration was 3 days.
Data source
Reference
- Title:
- Comparative effects of alicyclic compounds and quinones on inhibition of lettuce fruit germination.
- Author:
- REYNOLDS T.
- Year:
- 1 987
- Bibliographic source:
- Annals of Botany, 60, 215-223
Materials and methods
- Principles of method if other than guideline:
- other: Inhibition of germination test.
- Type : Agar substrate.
- Endpoint : Inhibition of fruit germination. - GLP compliance:
- not specified
Test material
- Reference substance name:
- Cyclopentanone
- EC Number:
- 204-435-9
- EC Name:
- Cyclopentanone
- Cas Number:
- 120-92-3
- Molecular formula:
- C5H8O
- IUPAC Name:
- cyclopentanone
- Details on test material:
- Test compound was used as received from the manufacturers (B.D.H. Chemicals Ltd., Sigma Chemical Co. Ltd. or Aldrich Chemical Co. Ltd.) without further purification.
Constituent 1
Test organisms
- Species:
- Lactuca sativa
Test conditions
- Details on test conditions:
- Test carried out at 30°C in ambient light.
Agar 0.5% was used as a germination substrate and contained Cyclopentanone in solution.
Inhibitor activity expressed as the concentration required producing a 50% reduction in germination after 3 days at 30°C compared with water
controls
Results and discussion
Effect concentrations
- Duration:
- 3 d
- Dose descriptor:
- other: IC50
- Effect conc.:
- 59.72 other: mg/l
- Basis for effect:
- other: see freetext
- Details on results:
- The concentration of Cyclopentanone which lower the percentage germination of lettuce fruits at 30°C to 50% of the control value was 59.72 +/- 18.5 mg/L (0.71 mM +/- 0.22)
Applicant's summary and conclusion
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